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PNI versus SCI: the acute neuronal-specific transcriptional responses after lesion

Correia, Patrícia D.; Estrada, Veronica; Reis, Andreia; Ramos, Sara; Moura, Gabriela; Müller, Hans Werner; Bosse, Frank; Vieira, Sandra

Spinal cord injury (SCI) has devastating functional consequences to patients, but lacks effective treatment. Peripheral nerve injury (PNI) is a widely used model to discover new regeneration associated genes (RAGs). Various transcriptomic studies have profiled injured spinal cord or sciatic nerve tissues aiming to discover new RAGs. However, it is difficult to depict neuronal-specific responses from whole-tissu...


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