2 documents found, page 1 of 1
Reduced numbers of regulatory T cells in chronic heart failure seems not to be ...
Martins, Sílvia; António, Natália; Carvalheiro, Tiago; Laranjeira, Paula; Rodrigues, Ricardo; Gonçalves, Lino; Tomaz, Cândida; Paiva, ArturBackground T cells have been implicated in the development and progression of inflammatory processes in chronic heart failure (CHF). Cardiac resynchronization therapy (CRT) has beneficial effects on symptoms and cardiac remodeling in CHF. However, its impact on the inflammatory immune response remains controversial. We aimed to study the impact of CRT on T cells in heart failure (HF) patients. Methods Thirty-ni...
Molecular Beacon Assay Development for Severe Acute Respiratory Syndrome Corona...
Carvalho, Josué; Nunes, J. Lopes; Figueiredo, Joana; Santos, Tiago; Miranda, André; Riscado, Micaela; Sousa, Fani; Duarte, A. P.; Socorro, SílviaThe fast spread of SARS-CoV-2 has led to a global pandemic, calling for fast and accurate assays to allow infection diagnosis and prevention of transmission. We aimed to develop a molecular beacon (MB)-based detection assay for SARS-CoV-2, designed to detect the ORF1ab and S genes, proposing a two-stage COVID-19 testing strategy. The novelty of this work lies in the design and optimization of two MBs for detect...