Habitat segregation is considered the mostprevalent resource-partitioning mechanism for streamfishes and the species morphology can be a strongpredictor of their spatial distribution. However, moststudies addressing morphology-habitat relationshipshave defined the space in physiognomically homoge-neous units (i.e., mesohabitat), probably not detectingsegregation among several closely related species. Herewe inv...
Sepsis is a complex disease and is the cause of many deaths worldwide. Sepsis pathogenesis involves a dysregulated inflammatory response with consequent production of inflammatory mediators and reactive species. The production and excessive release of these substances into the systemic circulation trigger various cellular and metabolic alterations that are observed during the disease evolution. Thus, more studi...
The metabolism of ethanol occurs mainly in the liver, promoting increase of reactive oxygen species and nitrogen, leading to redox imbalance. Therefore, antioxidants can be seen as an alternative to reestablish the oxidizing/reducing equilibrium. The aim of this study was to evaluate the antioxidant and hepatoprotective effect of aqueous extract of Baccharis trimera (Less.) DC., Asteraceae, in a model of hepato...
This study aimed to investigate the potential of an oral formulation (QV formulation) containing Quercetin and a Dipeptidyl Peptidase-4 Inhibitor (DPP-4 inhibitor), Vildagliptin, in improving metabolic homeostasis in type 1 diabetes model. Female albino Fischer rats were divided into four groups: untreated control animals (C), untreated diabetic animals (D), diabetic animals treated with QV formulation (DQV), a...
Programa de Pós-Graduação em Ciências Biológicas. Núcleo de Pesquisas em Ciências Biológicas, Pró-Reitoria de Pesquisa de Pós Graduação, Universidade Federal de Ouro Preto.; Diabetes Mellitus (DM) é uma doença metabólica caracterizada por hiperglicemia crônica e alterações no metabolismo de carboidratos, lipídeos e proteinas. Esta desordem leva a uma diminuição na atividade das enzimas antioxidantes, induz dano...
Aim: The aim of this study was to identify the effects of swimming training on the mRNA expression and protein levels of the calcium handling proteins in the hearts of renovascular hypertensive rats submitted to swimming protocol during 6 weeks. Main methods: Fischer ratswith renovascular hypertension 2-kidney 1-clip (2K1C) and SHAMgroups were divided among sedentary and exercised groups. The exercise protocol ...
Muitos estudos têm abordado a via conhecida como não genômica da aldosterona. Estes trabalhos mostram um grande número de atividades fisiológicas desse hormônio, que não envolvem o mecanismo clássico para receptores MR, no qual, ocorre a translocação do complexo hormônio-receptor ao núcleo. Ensaios realizados em culturas primárias de cardiomiócitos de ratos, na presença do inibidor do receptor MR, demonstraram ...