5 documents found, page 1 of 1
Quinolines: Microwave-assisted synthesis and their antifungal, anticancer and r...
Liberto, Natália Aparecida; Simões, Juliana Baptista; Silva, Sarah de Paiva; Fernandes, Sergio Antonio; Silva, Cristiane Jovelina daAn efficient method for the synthesis of quinolines using microwave irradiation was developed providing 28 quinolines with good yields. The reaction procedures are environmentally friendly, convenient, mild and of easy work-up. Quinolines were evaluated for their antifungal, anticancer and antioxidant properties and exhibited high activities in all tests performed.
p-Sulfonic acid calixarenes as efficient and reusable organocatalysts for the s...
Silva, Daniel L. da; Fernandes, Sergio A.; Sabino, Adão A.; Fátima, Ângelo deA new and efficient methodology is proposed for obtaining 3,4-dihydropyrimidin-2(1H)-ones/-thiones through Biginelli reactions. It is based on the use of less than the stoichiometric amount of p-sulfonic acid calixarenes as organocatalysts. A number of aromatic aldehydes as well as urea or thiourea can be employed for successfully synthesizing the corresponding Biginelli adducts. The described methodology is de...
β-Cyclodextrin-assisted synthesis of Biginelli adducts under solvent-free condi...
Liberto, Natália Aparecida; Silva, Sarah de Paiva; Fátima, Ângelo de; Fernandes, Sergio AntonioA simple, green and efficient protocol was developed using b -cyclodextrin as a solid catalyst for the solvent-free synthesis of various Biginelli adducts. The advantages of our protocol included the following: (i) a metal-free methodology; (ii) high yields; (iii) simple and efficient work-up procedures; (iv) improved results under solvent-free conditions. b -cyclodextrin-catalyzed the Biginelli reactions for v...
Organocatalysis in the three-component Povarov reaction and investigation by ma...
Simões, Juliana Baptista; Fátima, Ângelo de; Sabino, Adão Aparecido; Aquino, Francisco José Tôrres de; Silva, Daniel Leite daA diastereoselective three-component cascade reaction, catalyzed by p-sulfonic acid calix[4]arene, provides a unique method to access diverse julolidine derivatives in high yields. Additionally, the reaction was also monitored by mass spectrometry and the mechanistic pathway uncovered.
Copper(II) Nitroaromatic Schiff Base Complexes: Synthesis, Biological Activity ...
Martins, Darliane A.; Bomfim Filho, Lucius F.; Silva, Cleiton M. da; Fátima, Ângelo de; Louro, Sonia R. W.; Batista, Denise G. J.Universidade Federal de Minas Gerais. Departamento de Química. Belo Horizonte, MG, Brasil.; Universidade Federal de Minas Gerais. Departamento de Química. Belo Horizonte, MG, Brasil.; Universidade Federal de Minas Gerais. Departamento de Química. Belo Horizonte, MG, Brasil.; Universidade Federal de Minas Gerais. Departamento de Química. Belo Horizonte, MG, Brasil.; Pontifícia Universidade Católica do Rio de Jan...