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Role of rutin in 5-Fluorouracil-induced intestinal mucositis : prevention of hi...

Fideles, Lázaro de Sousa; Miranda, João Antônio Leal de; Martins, Conceição da Silva; Barbosa, Maria Lucianny Lima; Pimenta, Helder Bindá

Intestinal mucositis, characterized by inflammatory and/or ulcerative processes in the gastrointestinal tract, occurs due to cellular and tissue damage following treatment with 5-fluorouracil (5-FU). Rutin (RUT), a natural flavonoid extracted from Dimorphandra gardneriana, exhibits antioxidant, anti-inflammatory, cytoprotective, and gastroprotective properties. However, the effect of RUT on inflammatory process...

Date: 2021   |   Origin: Oasisbr
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