Mast cell tumors (MCT) are among the most common neoplasia in dogs, representing up to 21 % of skin tumors. However, etiology and risk factors for its development remain unclear. This study aimed to reduce this knowledge gap by comprehensively analyzing 905 MCT cases diagnosed in Portugal between 2019 and 2021, using descriptive and inferential analyses. Most tumors affected the skin, with 69.9 % and 21.2 % cla...
Breast cancer is a leading cause of cancer deaths among women worldwide and comprehends a group of heterogeneous tumors with variable prognosis. A strong investment was made over time and several therapeutic options were proposed. Conventional treatments are still based on surgery and chemo- and radiation therapy, which are generally associated with high invasiveness, extensive side effects and low specificity....
The animal cancer burden is essential for the translational value of companion animals in comparative oncology. The present work aims to describe, analyze, and compare frequencies and associations of tumors in dogs and cats based on the Animal Cancer Registry created by Vet-OncoNet. With 9079 registries, regarding 2019 and 2020, 81% (n = 7355) belonged to dogs. In comparison, cats have a general one-year right ...
Cutaneous mast cell tumour (MCT) Patnaik and Kiupel grading schemes rely on qualitative and semiquantitative features susceptible to interobserver variability. Stereological estimation of volume-weighted mean nuclear volume (MNV) provides information about both size and variability of nuclear size, which has been proven to have a prognostic value in other solid tumours. The objective was to compare MNV with MCT...
STEREOLOGICAL ESTIMATION OF MEAN NUCLEAR VOLUME AS A PROGNOSTIC FACTOR IN CANINE MAST CELL TUMOURS M. Casanova*, S. Branco*, I. Veiga† and P. Faísca‡ *Departamento de Medicina Veterinária, Universidade de Évora, Évora, Portugal, †Institut für Tierpathologie, Vetsuisse Bern, Bern, Switzerland and ‡Histopathology Unit, Instituto Gulbenkian de Ciência, Oeiras, Portugal Introduction: Cutaneous Mast Cell Tumour (MCT...
In Portugal, Veterinary Pathology is developing rapidly, and in recent years we assist to the emergence of private laboratories and the restructuring of universities,polytechnics and public laboratories.The Portuguese Society of Animal Pathology,through its actions and its associates has been keeping the discussion among its peers in order to standardizethe criteria of description,classification and evaluation ...