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Profile of cognitive impairment in late-stage Parkinson's disease

Sousa, Catarina Severiano e; Fabbri, Margherita; Godinho, Catarina; Simões, Rita Moiron; Chendo, Inês; Coelho, Miguel; Martins, Isabel Pavão

Introduction: The profile of cognitive impairment associated with the late stages of Parkinson's disease (LSPD) is rarely reported. Its characterization is necessary to better understand the cognitive changes that occur as the disease progresses and to better contribute to its management.


Motivos de exclusão para a cirurgia de estimulação cerebral profunda na doença ...

Carvalho, Miguel de Oliveira; Cattoni, Maria Begoña; Guedes, Leonor Correia; Carvalho, Herculano; Lobo, Patricia Pita; Albuquerque, Luisa


Profile of cognitive impairment in late‐stage Parkinson's disease

Severiano e Sousa, Catarina; Fabbri, Margherita; Godinho, Catarina; Moiron Simões, Rita; Chendo, Inês; Coelho, Miguel; Martins, Isabel Pavão

Introduction: The profile of cognitive impairment associated with the late stages of Parkinson's disease (LSPD) is rarely reported. Its characterization is necessary to better understand the cognitive changes that occur as the disease progresses and to better contribute to its management. Methods: In this cross-sectional study, we characterized the cognitive profile of LSPD patients using the comprehensive asse...


Profile of cognitive impairment in late-stage Parkinson's disease

Sousa, Catarina Severiano e; Fabbri, Margherita; Godinho, Catarina; Simões, Rita Moiron; Chendo, Inês; Coelho, Miguel; Martins, Isabel Pavão

Introduction: The profile of cognitive impairment associated with the late stages of Parkinson's disease (LSPD) is rarely reported. Its characterization is necessary to better understand the cognitive changes that occur as the disease progresses and to better contribute to its management. Methods: In this cross-sectional study, we characterized the cognitive profile of LSPD patients using the comprehensive asse...


High frequency of psychosis in late-stage Parkinson’s disease

Chendo, Inês; Fabbri, Margherita; Godinho, Catarina; Simões, Rita Moiron; Sousa, Catarina Severiano; Coelho, Miguel; Voon, Valerie; Ferreira, Joaquim J.

Background Psychosis is a frequent non-motor symptom in Parkinson’s disease (PD). Estimates of the frequency of Parkinsońs disease psychosis (PDP) vary widely. Knowledge about the frequency and phenomenology of psychosis in late-stage (LS) PD patients is limited. This study aimed to determine the frequency of psychosis in LSPD patients through clinical diagnostic interview (CDI) (gold standard), according to NI...


Clinical diagnostic criteria have a high impact on the frequency of dementia in...

Sousa, Catarina Severiano e; Fabbri, Margherita; Godinho, Catarina; Simões, Rita; Chendo, Inês; Coelho, Miguel; Martins, Isabel Pavão

Background: Cognitive impairment is a potential late feature of Parkinson's disease (PD). However, studies in patients with late-stage PD are lacking due to the particular characteristics of this population.


Deep brain stimulation fine-tuning in Parkinson’s disease: short pulse width ef...

Fabbri, Margherita; Natale, Federico; Artusi, Carlo Alberto; Romagnolo, Alberto; Bozzali, Marco; Giulietti, Giovanni; Guimarães, Isabel

Background: subthalamic nucleus deep brain stimulation (STN-DBS) may have a detrimental effect on speech in Parkinson’s disease (PD) patients and new stimulation technologies may help in addressing this issue. Objective: to evaluate the STN-DBS acute effect of 30 μs pulse width (30PW) versus conventional 60 μs PW (60PW) on speech and identify the core features of voice modified by 30PW. Methods: seven STN-DBS t...


High frequency of psychosis in late-stage Parkinson's disease

Chendo, Inês; Fabbri, Margherita; Godinho, Catarina; Simões, Rita Moiron; Sousa, Catarina Severiano; Coelho, Miguel; Voon, Valerie; Ferreira, Joaquim J.

Background: Psychosis is a frequent non-motor symptom in Parkinson’s disease (PD). Estimates of the frequency of Parkinsońs disease psychosis (PDP) vary widely. Knowledge about the frequency and phenomenology of psychosis in late-stage (LS) PD patients is limited. This study aimed to determine the frequency of psychosis in LSPD patients through clinical diagnostic interview (CDI) (gold standard), according to N...


Clinical diagnostic criteria have a high impact on the frequency of dementia in...

Sousa, Catarina Severiano e; Fabbri, Margherita; Godinho, Catarina; Simões, Rita; Chendo, Inês; Coelho, Miguel; Martins, Isabel Pavão

Background: Cognitive impairment is a potential late feature of Parkinson's disease (PD). However, studies in patients with late-stage PD are lacking due to the particular characteristics of this population. Objectives: To evaluate the frequency of dementia in late-stage PD patients and to assess the impact of using different diagnostic criteria. Methods: We conducted a cross-sectional study to estimate the fre...


Moving towards integrated and personalized care in Parkinson's disease: a frame...

van Munster, Marlena; Stümpel, Johanne; Thieken, Franziska; Pedrosa, David; Antonini, Angelo; Côté, Diane; Fabbri, Margherita; Ferreira, Joaquim J

Delivering healthcare to people living with Parkinson's disease (PD) may be challenging in face of differentiated care needs during a PD journey and a growing complexity. In this regard, integrative care models may foster flexible solutions on patients' care needs whereas Parkinson Nurses (PN) may be pivotal facilitators. However, at present hardly any training opportunities tailored to the care priorities of P...


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