3 documents found, page 1 of 1
Molecular Docking Studies of Curcumin Analogues against SARS-CoV-2 Spike Protein
Nogueira, Jéssica R.; Verza, Flávia A.; Nishimura, Felipe; Das, Umashankar; Caruso, Ícaro P. [UNESP]; Fachin, Ana L.; Dimmock, Jonathan R.Made available in DSpace on 2022-04-29T08:33:12Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) is the etiologic agent of the current pandemic of coronavirus disease 2019 (COVID-19) that has inflicted the loss of thousands of lives worldwide. The coronavirus surface spike (S)...
Curcumin-cinnamaldehyde hybrids as antiproliferative agents against women’s can...
Anselmo, Daiane B. [UNESP]; Polaquini, Carlos R. [UNESP]; Marques, Beatriz C. [UNESP]; Ayusso, Gabriela M. [UNESP]; Assis, Letícia R. [UNESP]Made available in DSpace on 2022-05-01T08:44:43Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; Curcumin and cinnamaldehyde are natural products whose antineoplastic activity has been well explored in biological evaluations. However, their poor chemical stability under physiological conditions has been an obstacle to their use as therapeutic agents. Herein, we designed and synthesized two series o...
Antiproliferative and pro-apoptotic activities of 2′- and 4′-aminochalcones aga...
Santos, Mariana B. [UNESP]; Pinhanelli, Vitor C.; Garcia, Mayara A.R. [UNESP]; Silva, Gabriel; Baek, Seung J.; França, Suzelei C.; Fachin, Ana L.Made available in DSpace on 2018-12-11T17:13:30Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-01-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); In the present study, a series of 2′- and 4′-aminochalcones were synthesized and their antiproliferati...