30 documents found, page 1 of 3
Seasonal chemical evaluation of Miconia chamissois Naudin from Brazilian Savanna
Ferreira, Juliana de Freitas; Mera López, Manuel Humberto; Gomes, João Victor Dutra; Martins, Diegue Henrique Nascimento; Fagg, Christopher WilliamMiconia chamissois Naudin is a species from the Cerrado, which is being increasingly researched for its therapeutic potential. The aim of this study was to obtain a standardized extract and to evaluate seasonal chemical variations. Seven batches of aqueous extracts from leaves were produced for the standardization. These extracts were evaluated for total solids, polyphenol (TPC) and flavonoid content (TFC), vit...
Lycorine alkaloid and Crinum americanum L. (Amaryllidaceae) extracts display an...
Silva, Lorene Coelho; Correia, Amabel Fernandes; Gomes, João Victor Dutra; Romão, Wanderson; Motta, Larissa Campos; Fagg, Christopher WilliamCandida species are the main fungal agents causing infectious conditions in hospital patients. The development of new drugs with antifungal potential, increased efficacy, and reduced toxicity is essential to face the challenge of fungal resistance to standard treatments. The aim of this study is to evaluate the in vitro antifungal effects of two crude extracts of Crinum americanum L., a rich alkaloid fraction a...
Biological properties and phytochemical characterization from Miconia chamissoi...
Gomes, Lorena Ferreira; Martins, Diegue Henrique Nascimento; Silva, Sandra Marcia Mazutti da; Barros, Yuri Yabu de; Souza, Paula Monteiro deThe objective of this study was to evaluate biological and phytochemical properties of the aqueous extract from the leaves of Miconia chamissoisNaudin (AEMC). Phytochemical properties were assessed by analyzing the chromatographic profile and the polyphenol content of AEMC. Biological properties evaluation wasconducted based on cytotoxicity assay and by evaluating the antioxidant, antimicrobial, and enzymatic i...
Influence of in vitro micropropagation on lycorine biosynthesis and anticholine...
Costa, Gabriella Gusmão Pereira da; Silva, Cristian Aldemar Gasca; Gomes, João Victor Dutra; Torres, Amanda Gomes; Santos, Izulmé Rita ImaculadaHippeastrum goianum (Ravenna) Meerow, Amaryllidaceae, is an endemic species from the Cerrado, Brazil; there are only few studies about its chemistry or biological activity. This study aimed to investigate the occurrence of lycorine in extracts from in vitro H. goianum plantlets, as well as evaluate a possible inhibition of acetylcholinesterase. The ethanol extract of plantlets produced by in vitro seed germinat...
Biodiversity of β-carboline profile of banisteriopsis caapi and ayahuasca, a pl...
Santos, Beatriz Werneck Lopes; Oliveira, Regina Célia de; Oliveira, Julia Sonsin; Fagg, Christopher William; Barbosa, José Beethoven FigueiredoAyahuasca is a psychoactive infusion with a large pharmacological application normally prepared with Banisteriopsis caapi, which contains the monoamine oxidase inhibitors β-carbolines, and Psichotria virids, which contains the serotonin receptor agonist N,N dimethyltryptamine (DMT). The objectives of this study were to investigate the chemical profile of B. caapi and of ayahuasca collected in various Brazilian ...
Evaluation of the antimicrobial activity of silver nanoparticles obtained by mi...
Tormena, Renata Pascoal Illanes; Rosa, Eliane Vieira; Mota, Bruna de Fatima Oliveira; Chaker, Juliano Alexandre; Fagg, Christopher WilliamWe describe here a green method for the preparation of silver nanoparticles (AgNPs), by a microwave-assisted synthesis route using Handroanthus impetiginosus underbark extract, with antibacterial activity. After optimizing the synthesis parameters with a Box–Benhken designed experiment, samples were characterized by powder XRD, TEM, UV-Vis spectroscopy, FTIR and zetametry. Using the overall optimized conditions...
Morpho-anatomy of native species used as substitute of quina (Cinchona spp.) in...
Somavilla, Nádia Sílvia; Fagg, Christopher William; Brandão, Maria G. L.Esenbeckia febrifuga (A.St.-Hil.) A. Juss. ex Mart., Rutaceae, is known by several popular names including quina-do-mato. This name is a reference to the use of its bark as febrifuge and in the past was employed as a substitute of Cinchona sp. for treatment of malaria symptoms. This confusion may have been reinforced by the fact that the bark of these plants are similar in appearance and have a bitter taste. In...
Micromorphology of the upper anthecium in Mesosetum Steud. and related genera (...
Silva, Anádria Stéphanie da; Ribeiro, André Rodolfo de Oliveira; Sousa, Mayco Werllen dos Santos; Fagg, Christopher William; Falcão, RosanaMesosetum is a Neotropical genus with 25 species, and 21 of them occur in Brazil. Mesosetum forms a clade closely related with Keratochlaena rigidifolia and Tatianyx arnacites. The objective of this work was to establish the taxonomic value of the upper anthecium micromorphology for the group. A total of 96 specimens, representing all Mesosetum species (except M. wrightii), K. rigidifolia and T. arnacites were ...
Morpho-anatomy and chemical profile of native species used as substitute of qui...
Somavilla, Nádia Sílvia; Cosenza, Gustavo P.; Fagg, Christopher William; Brandão, Maria G. L.This research is part of a larger study of the Brazilian species that are commonly referred to as "quinas" and used as substitute of Cinchona species. In this study, we have performed the botanical characterization of the stem bark of Remijia ferruginea (A. St.-Hil.) DC., Rubiaceae, by morphological and anatomical description, and the analysis of its chemical profile. Stem bark is thin and has the color and the...
Florestas estacionais e áreas de ecótono no estado do Tocantins, Brasil : parâm...
Haidar, Ricardo Flores; Fagg, Jeanine Maria Felfili; Pinto, José Roberto Rodrigues; Dias, Ricardo Ribeiro; Damasco, GabrielO objetivo deste estudo foi descrever a riqueza, estrutura e diversidade de espécies arbóreas em áreas de Floresta Estacional e ecótono (Floresta Estacional/Floresta Ombrófila) no estado do Tocantins, buscando subsídios para a conservação, manejo florestal, compensação de reserva legal e recuperação ambiental, além de discutir as identidades fitogeográficas em comparação com outras florestas do Brasil. Em 18 ba...