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Comparison of ELISA and HPLC-MS methods for the determination of exenatide in b...

Pinho, A. R.; Fortuna, A.; Falcão, A. N.; Santos, A. C.; Seiça, R.; Estevens, C.; Veiga, F.; Ribeiro, A. J.

The development of biotechnology-based active pharmaceutical ingredients, such as GLP-1 analogs, brought changes in type 2 diabetes treatment options. For better therapeutic efficiency, these active pharmaceutical ingredients require appropriate administration, without the development of adverse effects or toxicity. Therefore, it is required to develop several quantification methods for GLP-1 analogs products, ...


Elemental and topographic characterization of LDPE based copolymeric films obta...

Ferreira, L. M.; Falcão, A. N.; Gil, M. H.

The preparation of PE-g-HEMA (polyethylene-grafted-hydroxyethyl methacrylate) films by 60Co gamma irradiation has been optimized to produce a new material suitable for bioapplications.; http://www.sciencedirect.com/science/article/B6TJN-4PKFGWY-1/1/ce67dece44bee190c7fdab19460ed6d3


Modification of LDPE molecular structure by gamma irradiation for bioapplications

Ferreira, L. M.; Falcão, A. N.; Gil, M. H.

The surface properties of low-density polyethylene (LDPE) can be modified by the grafting of 2-hydroxyethyl methacrylate (HEMA). This was done aiming at the production of new materials suitable for bioapplications. Samples with different monomer concentrations were prepared from LDPE particles by gamma irradiation, following different irradiation protocols, including irradiation in presence and absence of air. ...


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