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Kinetic profile of the transcriptome changes induced in the choroid plexus by p...

Marques, Fernanda; Sousa, João Carlos; Coppola, Giovanni; Falcão, Ana Luisa Mendanha; Rodrigues, Ana João; Geschwind, Daniel H.; Sousa, Nuno

The choroid plexus, being part of the blood-brain barriers and responsible for the production of cerebrospinal fluid, is ideally positioned to transmit signals into and out of the brain. This study, using microarray analysis, shows that the mouse choroid plexus displays an acute-phase response after an inflammatory stimulus induced in the periphery by lipopolysaccharide (LPS). Remarkably, the response is specif...


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