117 documents found, page 1 of 12

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Bee Venom-Loaded Niosomes as Innovative Platforms for Cancer Treatment: Develop...

Pinto, Maria Beatriz; Pires, Patrícia C.; Calhelha, Ricardo C.; Silva, Ana Rita; Sousa, Maria João; Vilas-Boas, Miguel; Falcão, Soraia; Veiga, Francisco

Despite past efforts towards therapeutical innovation, cancer remains a highly incident and lethal disease, with current treatments lacking efficiency and leading to severe side effects. Hence, it is imperative to develop new, more efficient, and safer therapies. Bee venom has proven to have multiple and synergistic bioactivities, including antitumor effects. Nevertheless, some toxic effects have been associate...

Date: 2024   |   Origin: Biblioteca Digital do IPB

Evaluating the quality, physicochemical properties, and biological activities o...

Filipe, Márcia Santos; Kowalczyk, Tomasz; Kukula-Koch, Wirginia; Wieczfinska, Joanna; Bangay, Gabrielle; Diaz-Lanza, Ana María; Cardoso, Rossana V.C.

Honey, a natural production of honeybees, underscores Turkey’s prominence as one of the world’s largest honey producers. The country’s diverse flora fosters optimal conditions for beekeeping, resulting in the production of exceptional-quality honey. Centauri® Honey is uniquely sourced from remote alpine regions in Turkey, characterized by bees that inhabit isolated caves with access to medicinal endemic flowers...

Date: 2024   |   Origin: Biblioteca Digital do IPB

Discrimination of Quercus pyrenaica honeydew honey through the volatile profile

Falcão, Soraia; Mouffok, Kheira; Vilas-Boas, Miguel

Honey is a natural product produced by Apis mellifera bees from the nectar of flowers, and called nectar honey, or secretions of plants or excretions produced by plant-sucking insects and called honeydew honey. The production of these honey can be observed in the north of the Iberian Peninsula, where forests of black oak (Quercus pyrenaica) exist, from the honeydew secretions produced in the plant, which result...

Date: 2023   |   Origin: Biblioteca Digital do IPB

Medicinal centauri honey: a promising ingredient?

Filipe, Márcia Santos; Pires, Tânia C.S.P.; Calhelha, Ricardo C.; Diaz-Lanza, Ana María; Vilas-Boas, Miguel; Falcão, Soraia; Rijo, Patrícia

Honey is a natural product with antioxidant and antimicrobial properties, has been used as a medicinal substance for centuries. Thisnatural product is main- ly composed of a supersaturated solution of sugars, containing low water con- tent and trace amounts of bioactive compounds. The flower source, climate, geographical origin, harvesting process and storage conditions are factors that influence the compositio...

Date: 2023   |   Origin: Biblioteca Digital do IPB

The impact of bee product incorporation on the processing properties, nutrition...

Ertosun, Seymanur; Falcão, Soraia; Aylanc, Volkan; Tomás, Andreia; Russo-Almeida, Paulo; Rodrigues, Paula; Vilas-Boas, Miguel

Consumers are making their lifestyle healthier by changing diet, so food producers are exploring the enrichment of daily products using natural additives with nutraceutical properties. The addition of bee products is a good example, enabling a positive input in nutrients at the same time that the phytochemical substances present on it, may add complementary bioactive functions. This study centred on formulating...

Date: 2023   |   Origin: Biblioteca Digital do IPB

In vitro biological activity and phenolic profile of selected portuguese monofl...

Machado, Alexandra M.; Marto, Joana; Gonçalves, Lídia Maria; Ribeiro, Helena Margarida; Duarte, Aida; Tomás, Andreia; Falcão, Soraia; Vilas-Boas, Miguel

Portuguese monofloral honeys from carob tree, chestnut, bell heather, eucalyptus, incense, orange, and strawberry tree, were evaluated in vitro for antimicrobial, antioxidant, wound healing, and cell viability effect, compared to manuka honey 850+. Antimicrobial activity was determined against Gram+-and Gram- bacteria and yeast. Antioxidants, wound healing, and cell viability effects were studied in the Human K...

Date: 2023   |   Origin: Biblioteca Digital do IPB

Phenolic profile of Castanea bee pollen from the northwest of the iberian penin...

Rodriguez-Flores, Maria Shantal; Escuredo, Olga; Seijo-Coello, M. Carmen; Rojo, Sergio; Vilas-Boas, Miguel; Falcão, Soraia

Bee pollen is a rich bee product, from the point of view of its nutritional and functional chemical characteristics. The chemical composition of bee pollen and its properties make this product an excellent food supplement for the human diet, due to its various functional bioactivities, such as having antioxidant, antibacterial, antifungal, and anti-inflammatory properties. These properties depend on the botanic...

Date: 2023   |   Origin: Biblioteca Digital do IPB

Differentiating between monofloral portuguese bee pollens using phenolic and vo...

Larbi, Samar; Aylanc, Volkan; Rodriguez-Flores, Maria Shantal; Calhelha, Ricardo C.; Barros, Lillian; Rezouga, Feriel; Seijo-Coello, M. Carmen

Nowadays, bee products are commended by consumers for their medicinal and dietary properties. This study aimed to differentiate between monofloral bee pollens originating from Portugal using phenolic and volatile profiles and investigate their antioxidant and cytotoxic activity. Total phenolic and flavonoid compounds were recorded between 2.9-35.8 mg GAE/g and 0.7-4.8 mg QE/g, respectively. The LC/DAD/ESI-MSn a...

Date: 2023   |   Origin: Biblioteca Digital do IPB

Beneficial effect of bee venom and its major components on facial nerve injury ...

Er-Rouassi, Hafsa; Bakour, Meryem; Touzani, Soumaya; Vilas-Boas, Miguel; Falcão, Soraia; Vidal, Catherine; Lyoussi, Badiâa

Peripheral nerve injury (PNI) is a health problem that affects many people worldwide. This study is the first to evaluate the potential effect of bee venom (BV) and its major components in a model of PNI in the mouse. For that, the BV used in this study was analyzed using UHPLC. All animals underwent a distal section-suture of facial nerve branches, and they were randomly divided into five groups. Group 1: inju...

Date: 2023   |   Origin: Biblioteca Digital do IPB

Centauri honey: a promising medicinal ingredient?

Filipe, Márcia Santos; Pires, Tânia C.S.P.; Calhelha, Ricardo C.; Diaz-Lanza, Ana María; Vilas-Boas, Miguel; Falcão, Soraia; Rijo, Patrícia

Honey is a natural product that has been used over the centuries as a medicine due to its biological activities. Centauri Cave Nymph Honey is a Cave honey extracted from 2500 meters high altitude above sea level from a deep cave by professional speleologists and is located at Caucasus Mountains of Turkey. The Apis mellifera Caucasica bee colony is located 50 kilometers away from human residences, ensuring its i...

Date: 2023   |   Origin: Biblioteca Digital do IPB

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