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Polyphenol-enriched extract incorporated into a total-etch adhesive system : ef...
Sousa, Ilza Maria de Oliveira, 1963-; Foglio, Mary Ann, 1960-Agradecimentos: The authors would like to thank the São Paulo Research Foundation – FAPESP (Process Number # 2017/08082-7) and CNPq (Process Number # 303367/21018-0; # 139516/2018-2; # 147814/2017-0) for the grants provided; Abstract: This study evaluated water sorption, solubility and compound release of 2.5% Arrabidaea chica polyphenolic extract (Ac) incorporated into the primer of a total-etch adhesive syste...
The role of spray-drying atmosphere on fridericia chica (bonpl.) L.G. Lohmann s...
Sousa, Ilza Maria de Oliveira, 1963-; Queiroz, Núbia de Cássia Almeida, 1987-; Braga, Lucia Elaine de Oliveira, 1981-; Foglio, Mary Ann, 1960-Agradecimentos: The authors A.L.T.G.R. and M.A.F thank CNPq for research productivity fellowship. The authors also thank the Chemical, Biological, and Agricultural Pluridisciplinary Research Center (CPQBA/ Unicamp) for the laboratory infrastructure; Abstract: Fridericia chica (Bonpl.) L.G. Lohmann (synonym Arrabidaea chica Verlot) is widely used in Brazilian folk medicine. Considering overcoming pitfalls of sca...
Artemisinins induce endoplasmic reticulum stress in acute leukaemia cells in vi...
Mancuso, Rubia Isler, 1990-; Azambuja, Juliana Hofstatter; Niemann, Fernanda Soares; Foglio, Mary Ann, 1960-; Saad, Sara Teresinha Olalla, 1956-Abstract: Loss of endoplasmic reticulum (ER) homeostasis leads to ER stress, thus prolonged activation can lead to apoptosis. Herein, artesunate (ART) induced ER stress in leukaemia cells, resulting in eIF2a phosphorylation, activation of transcription factor 4, subsequent CHOP upregulation and XBP1 splicing. Furthermore, in vitro cyclin/CDKs reduction induced G1-phase arrest. An in vivo xenograft model showed ...
Novel transdermal bioadhesive surfactant-based system for release and solubilit...
Zanutto, Fabiana Volpe, 1985-; Santos, Bruno da Fonseca dos; Foglio, Mary Ann, 1960-; Figueiredo, Mariana Cecchetto, 1980-Abstract: Artemether (ART) and lumefantrine (LUM) are the gold standard antimalarial drugs used for the treatment of malaria in children and pregnant women. Typically, ART and LUM are delivered orally in the form of a combined tablet, however, the appropriateness of this route of administration for these drugs is questionable due to the poor absorption and therefore bioavailability observed unless administered ...
Pterodon pubescens benth (sucupira) microencapsulation influence on formulation...
Coco, Julia Cedran, 1997-; Sousa, Ilza Maria de Oliveira, 1963-; Ataide, Janaína Artem, 1991-; Rodrigues, Rodney Alexandre Ferreira, 1964-Abstract: Pterodon pubescens Benth is a Brazilian native species, used in folk medicine for chronic pain relief. The anti-inflammatory, antinociceptive, and antiproliferative activities attributed to the species have a straight relationship with vouacapans (furanditerpenes) and geranylgeraniol (acyclic diterpenes), identified in P. pubescens extracts. Nevertheless, scarce reports are found on product developmen...
Bixa orellana L. by-products' fractions from an industrial process : antiprolif...
Basting, Rosanna Tarkany, 1989-; Abreu, Pedro Manoel Barreto de, 1996-; Sousa, Ilza Maria de Oliveira, 1963-; Carvalho, João Ernesto de, 1954-Abstract: This study evaluated the phytochemical characterization ofBixa orellana(BO extract) unsaponifiable extract and resulting fractions (F fraction - FF, Geranyl fraction - GF and R fraction- RF) obtained as by-products of an industrial process investigatingin vitroantiproliferative activities in human tumoral cells. The main compounds identified by GC-MS for BO extract were Geranylgeraniol (61.51%); for F...
Um estudo quimico da Artemisia annua L. aclimatada no Brasil
Foglio, Mary Ann, 1960-Orientador: Anita Jocelyne Marsaioli; Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Quimica; Doutorado