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Evaluation of the inflammatory response induced by different materials in the t...

Galvão,Mariana Ocampos; Santos,Carlos Henrique Marques dos; Falcão,Gustavo Ribeiro

ABSTRACT The medical literature has no study evaluating the effectiveness of different materials used as setons in the treatment of perianal fistulas; therefore, there is no evidence of availability of a more effective material than others for this purpose. OBJECTIVE: To evaluate the inflammatory response induced by different materials used as seton in perianal fistulas in rats. METHOD: Thirty Wistar rats, whic...

Date: 2016   |   Origin: Oasisbr

Late diagnosis of Hirschsprung's disease

Martins,Marielle Rodrigues; Santos,Carlos Henrique Marques dos; Falcão,Gustavo Ribeiro

ABSTRACTHirschsprung's disease is a condition characterized by the absence of ganglion cells in a variable segment of the large intestine, mainly producing the symptom of constipation and being usually diagnosed in the first year of life. With diagnostic methods already established in the literature, the sole treatment is surgery. The objective of this study is to report a case of late diagnosis of the disease a...

Date: 2015   |   Origin: Oasisbr

Ischemia and reperfusion of rat small intestine using pentoxyfilline and prosta...

Brasileiro,José Lacerda; Inoye,Celso Maschaschi; Aydos,Ricardo Dutra; Silva,Iandara Schettert; Falcão,Gustavo Ribeiro; Marks,Guido

PURPOSE: To investigate the small intestinal tissue alterations in rats submitted to ischemia and tissue reperfusion using pentoxyfilline or prostaglandin E1. METHODS: Thirty five Wistar rats were used, distributed into group control (A) n=10 were submitted to intestinal ischemia and reperfusion during 60 minutes and no one drug have been utilized. In the group pentoxyfilline (B) n=10 have been utilized during ...

Date: 2013   |   Origin: Oasisbr

Experimental model of anal fistula in rats

Arakaki,Mariana Sousa; Santos,Carlos Henrique Marques dos; Falcão,Gustavo Ribeiro; Cassino,Pedro Carvalho; Nakamura,Ricardo Kenithi

INTRODUCTION: the management of anal fistula remains debatable. The lack of a standard treatment free of complications stimulates the development of new options. OBJECTIVE: to develop an experimental model of anal fistula in rats. METHODS: to surgically create an anal fistula in 10 rats with Seton introduced through the anal sphincter musculature. The animals were euthanized for histological fistula tract asses...

Date: 2013   |   Origin: Oasisbr

S100, CD68, and MHC class II molecule expression in cervical high- and low-grad...

Cassandri,Fernanda; Tozetti,Inês Aparecida; Fernandes,Carlos Eurico dos Santos; Almeida,Flávia Gatto de; Falcão,Gustavo Ribeiro

INTRODUCTION: Some human papillomavirus (HPV) types are involved in malignant processes in the cervical epithelium, with 99% of cases attributed to oncogenic HPV infection. This study aimed to detect S100, CD68, and major histocompatibility complex class II (MHC-II) molecules in cervical uterine epithelial samples in patients with high- and low-grade lesions induced by HPV. METHODS: Fifty-eight samples from pat...

Date: 2012   |   Origin: Oasisbr

Linfócitos CD4, CD8 e células NK no estroma da cérvice uterina de mulheres infe...

Alves,Daniella Borges; Tozetti,Inês Aparecida; Gatto,Flávia Almeida; Cassandri,Fernanda; Ferreira,Alda Maria Teixeira

INTRODUÇÃO: A resposta imune pode ser um elemento chave para a progressão ou remissão da infecção pelo papilomavírus humano (HPV) no estroma da cérvice uterina. Este estudo objetivou quantificar no estroma cervical a presença de linfócitos T CD4, CD8 e células NK, por imunohistoquímica, em lesões de alto e baixo grau em pacientes infectadas por HPV MÉTODOS: Utilizou-se 56 amostras de biópsia da estroma cervical...

Date: 2010   |   Origin: Oasisbr

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