19 documents found, page 1 of 2
PCR-confirmed malaria among children presenting with a decreased level of consc...
Savonius, Okko; Souza, Cintia F. de; Fançony, Cláudia; Cruzeiro, Manuel Leite; Brito, Miguel; Pelkonen, TuulaBackground: In malaria-endemic areas, children presenting to hospitals with a decreased level of consciousness remain in a diagnostic dilemma. The definition of cerebral malaria in a comatose child demands the exclusion of other possible reasons, which requires in-depth investigations that are not easily available. The aim of this study was to investigate the frequency and clinical characteristics of PCR-confir...
Zinc Deficiency Interacts with Intestinal/Urogenital Parasites in the Pathway t...
Fançony, Cláudia; Soares, Ânia; Lavinha, João; Brito, MiguelIn host organisms with normal micronutrient status, nutritional immunity is a strongly regulated response aiming at decreasing the progression and severity of infections. Zinc deficiency may disturb this balance, impairing immune responses to infections, which may indirectly increase infection-related anemia. Since zinc deficiency may associate directly with anemia, the role of infections is often overlooked. H...
Zinc deficiency interacts with intestinal/urogenital parasites in the pathway t...
Fançony, Cláudia; Soares, Ânia; Lavinha, João; Brito, MiguelIn host organisms with normal micronutrient status, nutritional immunity is a strongly regulated response aiming at decreasing the progression and severity of infections. Zinc deficiency may disturb this balance, impairing immune responses to infections, which may indirectly increase infection-related anemia. Since zinc deficiency may associate directly with anemia, the role of infections is often overlooked. H...
Effectiveness of nutrition and WASH/malaria educational community-based interve...
Fançony, Cláudia; Soares, Ânia; Lavinha, João; Barros, Henrique; Brito, MiguelWe found no published data in Angola regarding the effect of combining nutrition-specific and nutrition-sensitive approaches in the reduction of anemia in preschool children. Thus, we implemented a cluster-randomized controlled trial to determine the effectiveness of two educational-plus-therapeutic interventions, in Nutrition and WASH/Malaria, in reducing anemia. We compared them to (1) a test-and-treat interv...
Schistosomiasis and soil-transmitted helminthiasis preventive chemotherapy: adv...
Lemos, Manuel; Pedro, João M.; Fançony, Cláudia; Moura, Sofia; Brito, Miguel; Nery, Susana Vaz; Sousa, Carlos Pinto; Barros, HenriquePreventive chemotherapy campaigns with praziquantel and albendazole are being implemented in Angola, as a high-priority public health intervention. However, there are no published data regarding adverse events associated with these medications. In this context, we analyzed adverse events due to co-administration of praziquantel and albendazole in endemic areas of schistosomiasis and soil-transmitted helminths i...
Integrated community-based intervention for urinary schistosomiasis and soil-tr...
Lemos, Manuel; Fançony, Cláudia; Moura, Sofia; Mirante, Clara; Sousa, Pinto de; Barros, Henrique; Nery, Susana; Brito, MiguelBackground: Schistosomiasis and soil-transmitted helminths (STH) infections are major public health problems. We aimed to study the 6-mo impact of mass drug administration with praziquantel and albendazole on urinary schistosomiasis and STH. Methods: We examined children (aged 2–15 y) from one hamlet, who provided urine and feces samples at baseline (n=197), 1 mo (n=102), and 6 mo (n=92); 67 completed the proto...
Iron deficiency anaemia among 6-to-36-month children from northern Angola
Fançony, Cláudia; Soares, Ânia; Lavinha, João; Barros, Henrique; Brito, MiguelBackground: Angola is one of the southern African countries with the highest prevalence of anemia. Identifying anemia determinants is an important step in the design of evidence-based control strategies. In this study, we aim at documenting the factors associated with Iron Deficiency Anaemia (IDA) in 948 children recruited at the Health Research Center of Angola study area during 2015. Methods: Data on demograp...
Anemia in preschool children from Angola
Fançony, Cláudia; Lavinha, João; Brito, Miguel; Barros, HenriqueAngola is one of the southern African countries with the highest prevalence of anemia, and despite the high geographic heterogeneity of its distribution across the country, it was reported to be indicative of a severe public health problem in some areas, mainly in children. Despite the relevance of this condition in the country, there is still an important gap regarding scientific evidence and knowledge systema...
Iron deficiency anaemia among 6-to-36-month children from northern Angola
Fançony, Cláudia; Soares, Ânia; Lavinha, João; Barros, Henrique; Brito, MiguelBackground: Angola is one of the southern African countries with the highest prevalence of anaemia. Identifying anaemia determinants is an important step for the design of evidence-based control strategies. In this study, we aim at documenting the factors associated with Iron Deficiency Anaemia (IDA) in 948 children recruited at the Health Research Center of Angola study area during 2015. Methods: Data on demog...
Anemia in preschool children from Angola: a review of the evidence
Fançony, Cláudia; Lavinha, João; Brito, Miguel; Barros, HenriqueAngola is one of the southern African countries with the highest prevalence of anemia, and despite the high geographic heterogeneity of its distribution across the country, it was reported to be indicative of a severe public health problem in some areas, mainly in children. Despite the relevance of this condition in the country there is still an important gap regarding scientific evidences and knowledge systema...