24 documents found, page 1 of 3
Antibacterial and Cytotoxic Activities of Copper-Functionalized Silsesquioxane ...
Pedroso,Flávia de Brito; Aguiar,Deize Basílio dos Santos de; Brito,Priscilla Salles de; Pessôa,Christiana Andrade; Fujiwara,Sérgio ToshioAbstract Silsesquioxane 3-n-propylpyridinium chloride (SiPy+Cl-) is a water-soluble polymer that can be used as a promising material with remarkable biological effects. SiPy+Cl- can form thin films on substrate surfaces and shows suitable adhesiveness. Besides, it has high affinity for metal ions. Considering this effect as exchanger polymer and the well-known antimicrobial and cytotoxic features of copper, the...
Analysis of diagnostic criteria for ventilator-associated pneumonia: a cohort s...
Campos,Caroline Gonçalves Pustiglione; Pacheco,Aline; Gaspar,Maria Dagmar da Rocha; Arcaro,Guilherme; Reche,Péricles Martim; Nadal,Jessica MendesABSTRACT Objectives: to analyze the diagnostic criteria for ventilator-associated pneumonia recommended by the Brazilian Health Regulatory Agency and the National Healthcare Safety Network/Centers for Disease Control and Prevention, as well as its risk factors. Methods: retrospective cohort study carried out in an intensive care unit throughout 12 months, in 2017. Analyses included chi-square, simple linear reg...
Coadministration of ibuprofen/caffeine on bleaching-induced tooth sensitivity: ...
Silva,Karine Letícia da; Sutil,Elisama; Hortkoff,Diego; Terra,Renata Maria Oleniki; Rezende,Márcia; Reis,Alessandra; Loguercio,Alessandro D.Abstract This clinical trial evaluated the effect of the coadministration of ibuprofen/caffeine on bleaching-induced tooth sensitivity (TS). A triple-blind, parallel-design, randomized clinical trial was conducted on 84 patients who received ibuprofen/caffeine or placebo capsules. The drugs were administered for 48 hours, starting 1 hour before the in-office bleaching. Two bleaching sessions were performed with...
Eucalyptus cinerea: Microscopic Profile, Chemical Composition of Essential Oil ...
Pauzer,Matheus Saukoski; Borsato,Thais de Oliveira; Almeida,Valter Paes de; Raman,Vijayasankar; Justus,Bárbara; Pereira,Camila BugnottoAbstract Eucalyptus species possess anti-inflammatory, antifungal, antibacterial, and insecticidal properties. In this study, the chemical composition and biological activities of Eucalyptus cinerea essential oil (EO) and the leaf and stem anatomy were investigated. EO was extracted by Clevenger apparatus and the compounds were identified by GC/MS. The antioxidant activity was evaluated by DPPH, ABTS, and reduc...
Liposomal anesthetic gel for pain control during periodontal therapy in adults:...
Moraes,Gustavo Simao; Santos,Isadora Benato dos; Pinto,Shelon Cristina Souza; Pochapski,Marcia Thais; Farago,Paulo Vitor; Pilatti,Gibson LuizAbstract Periodontal therapy usually requires local anesthesia. If effective, a non-invasive, liposomal anesthetic gel could increase the levels of acceptance of patients in relation to periodontal therapy. Objective: This study investigated the efficacy of liposomal anesthetic gel for pain control during periodontal therapy. Methodology: Forty volunteers with moderate to severe chronic periodontitis were recru...
Effect of Cilostazol-Loaded PCL/PEG Nanocapsules on Abdominal Aortic Tunics and...
Pilatti,Luís Daniel Silva; Rodrigues,Ricardo; Nascimento,Núbia da Silva; Gomes,Mona Lisa Simionatto; Zanin,Sandra Maria Warumby; Farago,Paulo VitorAbstract Cilostazol (CLZ) is a phosphodiesterase III inhibitor with antiplatelet and vasodilator properties. It has been recently verified that CLZ plays a significant role in the arteries by inhibiting the proliferation and growth of muscle cells, increasing the release of nitric oxide by the endothelium and promoting angiogenesis. Considering these promising effects, the use of nanocapsules may be an interest...
PEG-PCL Nanocapsules Containing Curcumin: Validation of HPLC Method for Analyzi...
Rudnik,Loanda Aparecida Cabral; Lyra,Amanda Martinez; Barboza,Fernanda Malaquias; Klein,Traudi; Kanunfre,Carla Cristine; Farago,Paulo VitorAbstract Curcumin (CUR) shows potential use for treating cancer. However, CUR has low solubility and reduced bioavailability, which limit its clinical effect. Therefore, the development of nanocarriers can overcome these problems and can ensure the desired pharmacological effect. In addition, it is mandatory to prove the quality, the efficacy, and the safety for a novel nanomedicine to be approved. In that sens...
Ocotea porosa: Anatomy and Histochemistry of Leaves and Stems, Chemical Composi...
Brustulim,Libardone José Ribeiro; Monteiro,Luciane Mendes; Almeida,Valter Paes de; Raman,Vijayasankar; Maia,Beatriz Helena Lameiro de Noronha SalesAbstract Ocotea porosa (Nees & Mart.) Barroso, commonly known as “imbuia”, “canela-imbuia” or “imbuia-amarela” in Brazil, is a tree of the Southern Atlantic Forest. The present study investigates the anatomy of leaf and stem, volatile oil chemistry, as well as cytotoxicity and insecticidal activities of the essential oil of O. porosa. Species identification was achieved by anatomy features, mainly due to paracy...
Characterization and Cytotoxic Evaluation of Silver and Gold Nanoparticles Prod...
Justus,Barbara; Arana,Andrés Fernando Montenegro; Gonçalves,Melissa Marques; Wohnrath,Karen; Boscardin,Patrícia Mathias Döll; Kanunfre,Carla CristineAbstract Metallic nanoparticles have great potential as a chemotherapeutic agent. The aim of this study was to develop and characterize silver and gold nanoparticles using a simple method, as well as evaluating the potential cytotoxic activity in relation to the K-562 cell line. For the synthesis, a solution containing the metallic ions was subjected to magnetic stirring with the aqueous extract of Lavandula de...
Anatomy and volatile oil chemistry of Eucalyptus saligna cultivated in South Br...
Saulle,Carolina Ceriani; Raman,Vijayasankar; Oliveira,Adrian Vriesman Gabriel; Maia,Beatriz Helena Lameiro de Noronha Sales; Meneghetti,Emanuelle KretzABSTRACT Eucalyptus saligna Sm., Myrtaceae, commonly known as Sydney blue gum, is often confused with several other species in the genus. The leaf volatile oils of the species have been reported to have antimicrobial, insecticidal, nematicidal, repellent and cytotoxicity properties. The present work provides anatomy as well as volatile oil chemistry of the species collected from South Brazil. The anatomy and hi...