2 documents found, page 1 of 1
Gla Rich Protein (GRP) Mediates Vascular Smooth Muscle Cell (VSMC) Osteogenic D...
Viegas, Carla; Carreira, Joana; Maia, Teresa M.; Macedo, Anjos L.; Matos, António P.; Neves, José; Simes, Dina7); by AAC No. 41/ALG/2020—Project No. 072583—NUTRISAFE; and by the Portuguese Society of Nephrology (SPN) through projects funding 2019. Publisher Copyright: © 2024 by the authors. Licensee MDPI, Basel, Switzerland.; Vascular calcification (VC) is a complex process involving vascular smooth muscle cell (VSMC) osteogenic differentiation, inflammation, and extracellular vesicle (EV) calcification and communicati...
Nanoencapsulation of Gla-Rich Protein (GRP) as a Novel Approach to Target Infla...
Viegas, Carla S. B.; Araújo, Nuna; Carreira, Joana; Pontes, Jorge F.; Macedo, Anjos L.; Vinhas, Maurícia; Moreira, Ana S.; Faria, Tiago Q.; Grenha, AnaLA/P/0101/2020 LA/P/0140/2020 AAC nº 41/ALG/2020—Project nº 072583—NUTRISAFE; Chronic inflammation is a major driver of chronic inflammatory diseases (CIDs), with a tremendous impact worldwide. Besides its function as a pathological calcification inhibitor, vitamin K-dependent protein Gla-rich protein (GRP) was shown to act as an anti-inflammatory agent independently of its gamma-carboxylation status. Although ...