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Sustainable valorization of wheat by-products through a green bioprocessing

Ferreira, Daniela Marisa; Brassesco, Maria Emília; Coscueta, Ezequiel; Pintado, Manuela

Cereals, particularly wheat, are a fundamental part of the global diet, but their processing generates significant by-products, namely wheat bran (WB) and wheat germ (WG), yielding, annually and globally, approximately 150 million tonnes and 25 million tonnes of by-products, respectively. These by-products remain largely underutilized. Wheat bran is a valuable source of dietary fiber and minerals, while wheat g...


Intestinal mucosal alterations parallel central demyelination and remyelination...

Ferreira, Carolina; Carvalho, Filipa; Vieira, Pedro; Alves, André; Palavra, Filipe; Almeida, Jani; Alves, Vera; Coscueta, Ezequiel

Background: The gut-brain axis has been increasingly recognized as a critical factor in Multiple Sclerosis (MS) pathophysiology. While its role in demyelination is well documented, gut-brain axis involvement during remyelination remains largely unexplored. Methods: Using the cuprizone (CPZ) model, which induces reversible demyelination and spontaneous remyelination upon toxin withdrawal, we investigated gut and...


A full insight into the valorization of wheat by-products

Ferreira, Daniela Marisa; Coscueta, Ezequiel; Brassesco, María Emília; Pintado, Manuela

Wheat is one of the most consumed cereals globally, significantly contributing to human nutrition [1]. However, wheat processing generates underutilized by-products, primarily wheat germ and bran, despite their high nutritional value [2][3]. Wheat bran (WB) is a primary source of dietary fiber, proteins, and phenolic compounds and contributes to approximately 25% of the total weight of the wheat grain [4]. Ther...


A full insight into the valorization of wheat by-products

Ferreira, Daniela Marisa; Coscueta, Ezequiel; Brassesco, María Emília; Pintado, Manuela

Wheat is one of the most consumed cereals globally, significantly contributing to human nutrition [1]. However, wheat processing generates underutilized by-products, primarily wheat germ and bran, despite their high nutritional value [2], [3]. Wheat bran (WB) is a primary source of dietary fiber, proteins, and phenolic compounds and contributes to approximately 25% of the total weight of the wheat grain [4]. Th...


Harnessing agrifood by-products for sustainable protein development: a focus on...

Paupério, Ana Isabel; Brassesco, María Emilia; Coscueta, Ezequiel; Ferreira, João Paulo; Pintado, Manuela


SE-HPLC as a tool to guide the production of novel peptide fractions for textil...

Bonifácio-Lopes, Teresa; Afonso, Tiago Barros; Coscueta, Ezequiel; Costa, Eduardo; Pintado, Manuela

As the need for more bio centered solutions within the textile industry, complex increases it has been the role of R&D industries and academia to find within themselves tools that can guide the discovery and development of biobased products and solutions. One technique that nowadays plays a key role in the sustainable development of novel textile solutions is Size Exclusion HPLC (SE-HPLC). While on its core SE-...


Revealing the potential brewer’s spent yeast: sustainable innovations for alter...

Brassesco, María Emilia; Paupério, Ana Isabel; Coscueta, Ezequiel; Pereira, Carlos D.; Ferreira, João Paulo; Pintado, Manuela

Background: Brewer’s spent yeast (BSY), the second most significant by-product of the brewing industry, represents an abundant biomass resource with considerable environmental implications due to its annual accumulation. This study aims to valorize BSY by-products producing differentiated functional extracts that can be used to formulate protein-rich snacks. By enhancing the value of this by-product, the resear...


Revealing the potential brewer’s spent yeast: sustainable innovations for alter...

Brassesco, María Emilia; Paupério, Ana Isabel; Coscueta, Ezequiel; Pereira, Carlos D.; Ferreira, João Paulo; Pintado, Manuela

Introduction: Brewer’s spent yeast (BSY), a major brewing by-product, accumulates annually, posing environmental challenges [1]. Research highlights BSY’s potential as a sustainable alternative protein source in animal feed and human food. With the market expected to reach $2.17 billion by 2030, BSY offers a promising solution for waste reduction and protein replacement. However, more research is needed to opti...


A circular economy approach to leather by products valorization towards a zero-...

Bonifácio-Lopes, Teresa; Afonso, Tiago Barros; Coscueta, Ezequiel; Costa, Eduardo M.; Pintado, Manuela

Introduction: The tanning industry has a significant waste production and is a major contributor to environmental pollution; The adoption of circular economy principles will help repurposing by-products with a focus on reutilizing leather remnants; With this approach, the objective is to minimize environmental damage and effectively manage waste; This will contribute to sustainability with a reduction of overal...


Defatted nannochloropsis oculata biomass: waste or resource?

Sousa, Sérgio; Machado, Manuela; Coscueta, Ezequiel; Ferreira, Andreia S.; Nunes, Cláudia; Coimbra, Manuel A.; Freitas, Ana C.; Carvalho, Ana P.

Microalgae are recognized as a valuable source of a panoply of compounds. In addition to the extensively investigated lipid fraction comprising polyunsaturated fatty acids (PUFA), microalgae biomass also encompasses other compounds with potentially relevant biological activities. This work innovatively repurposes the defatted biomass (DB) of Nannochloropsis oculata, highlighting its potential value beyond the l...


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