3 documents found, page 1 of 1
Pancreatic stone protein as a biomarker of sepsis
Lopes, Diogo; Chumbinho, Beatriz; Bandovas, João Pedro; Faria, Pedro; Espírito Santo, Catarina; Ferreira, Bernardo; Val-Flores, Luis; Pereira, Rui
3′Nucleotidase/nuclease is required for Leishmania infantum clinical isolate su...
Carniellie, Juliana; Dave, Anuja; Romano, Audrey; Forrester, Sarah; Faria, Pedro; Renata, Monti-Rocha,; Costa, Carlos; Dietze, R; Graham, IanSummary Background Miltefosine treatment failure in visceral leishmaniasis in Brazil has been associated with deletion of the miltefosine susceptibility locus (MSL) in Leishmania infantum. The MSL comprises four genes, 3′ -nucleotidase/nucleases (NUC1 and NUC2); helicase-like protein (HLP); and 3,2-trans-enoyl-CoA isomerase (TEI). Methods In this study CRISPR-Cas9 was used to either epitope tag or delete NUC1, ...
COVID-19 symptoms at hospital admission vary with age and sex
Abdukahil, Sheryl Ann; Abe, Ryuzo; Abel, Laurent; Absil, Lara; Acker, Andrew; Adachi, Shingo; Adam, Elisabeth; Adriao, Diana; Ainscough, KateFunding This work was supported by the Department for International Development and Wellcome Trust [215091/Z/18/Z]; the Bill and Melinda Gates Foundation [OPP1209135]. Country-specifc support was provided by the Canadian Institutes of Health Research Coronavirus Rapid Research Funding Opportunity [OV2170359]; the Health Research Board Ireland [CTN Award 2014-012]; National Institute for Health Research (NIHR) [...