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Molecular Beacon Assay Development for Severe Acute Respiratory Syndrome Corona...

Carvalho, Josué; Nunes, J. Lopes; Figueiredo, Joana; Santos, Tiago; Miranda, André; Riscado, Micaela; Sousa, Fani; Duarte, A. P.; Socorro, Sílvia

The fast spread of SARS-CoV-2 has led to a global pandemic, calling for fast and accurate assays to allow infection diagnosis and prevention of transmission. We aimed to develop a molecular beacon (MB)-based detection assay for SARS-CoV-2, designed to detect the ORF1ab and S genes, proposing a two-stage COVID-19 testing strategy. The novelty of this work lies in the design and optimization of two MBs for detect...

Date: 2021   |   Origin: uBibliorum

2014/2015 Influenza season in an inland portuguese region

Almeida, Sofia; Rodrigues, Débora; Gouveia, Paula; Paulo, Sandra; Faria, Conceição; Pechirra, Pedro; Costa, Inês; Cristóvão, Paula; Guiomar, Raquel

Influenza surveillance is an important tool to identify emerging/reemerging strains, and defining seasonality of the circulating strains. The aim of this work is to compare the circulating strains detected by Centro Hospitalar da Cova da Beira, EPE,(CHCB) from an inland north region of Portugal, with the strains circulating among Europe during2014/2015 Influenza season. In the present review, 249 nasofaringeal ...


Hemorragia Intraperiventricular no Recém-Nascido de Muito Baixo Peso 1994-1996

Nona, José; Lança, Isabel; Birne, Álvaro; Faria, Conceição; Valido, A. Marques

Objectivos: Avaliar a incidência de HIPV/IPE no RN MBP e a sua correlação com o desenvolvimento neuromotor após os 12 meses de idade corrigida. Material e Métodos: Foi efectuada a análise retrospectiva de todos os processos clínicos dos RN MBP com diagnóstico ecotomográfico de HIPV internados na UCIN da MAC durante 3 anos consecutivos (01/01/1994 a 31/12/1996). Foram utilizadas as classificações de Volpe e de P...


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