2 documents found, page 1 of 1
Ticagrelor Loading on ST-Elevation Myocardial Infarction: Interaction With Prod...
Faria, JP; Oliveira, P; Alexandre, A; Couto, DS; Costa, R; Campinas, A; Frias, A; Brochado, B; Santos, R; Silveira, J; Torres, S; Luz, AIntroduction:Ticagrelor might reduce infarct size by exerting a more potent antiplatelet effect or by promoting a potential conditioning stimulus in ST-elevation myocardial infarction (STEMI) patients. Pre-infarction angina (PIA) is an effective preconditioning stimulus that reduces ischemia-reperfusion injury. Because little is known on the interaction of PIA in STEMI-patients loaded with ticagrelor, we sought...
Modulation of oligodendrocyte differentiation and maturation by combined bioche...
Lourenço, T; Faria, JP; Bippes, C; Maia, J; Lopes-Da-Silva, J; Relvas, JB; Graõs, MExtracellular matrix (ECM) proteins play a key role during oligodendrogenesis. While fibronectin (FN) is involved in the maintenance and proliferation of oligodendrocyte progenitor cells (OPCs), merosin (MN) promotes differentiation into oligodendrocytes (OLs). Mechanical properties of the ECM also seem to affect OL differentiation, hence this study aimed to clarify the impact of combined biophysical and bioche...