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Effect of skimmed milk on intestinal tract: prevention of increased reactive ox...

Pinho, Susana C. M.; Faria, Miguel A.; Melo, Armindo; Pinto, Edgar; Almeida, Agostinho; Alves, Rui; Cabrita, Ana R. J.; Fonseca, António J. M.

The capacity of skimmed milk to neutralise increased reactive oxygen species (ROS) and to attenuate nitric oxide (NO) production, as well as to present cytoprotective effect at the intestinal level was assessed after in vitro gastro-intestinal digestion. The impact on ROS modulation was evaluated at a non-cytotoxic concentration of hydrogen peroxide (H2O2) in a co-culture of Caco-2 and HT-29 intestinal cells. I...


Whole meals nutritional composition: comparison between experimental and theore...

Ribeiro, Mafalda; Silva, Marta; Viegas, Olga; Martins, Zita; Casal, Susana; Mendes, Eulália; Pinto, Edgar; Faria, Miguel A.; Ferreira, Isabel MPLVO

Information concerning food composition is essential in public health and nutrition. Chemical analyses are the most accurate methodologies for the assessment of food composition, however, these procedures are very expensive and time-consuming. Therefore, food composition data has been compiled in databases to facilitate the access and manipulation of information. Although food composition databases (FCDB) are v...


Nutritional quality of protein concentrates from Moringa Oleifera leaves and in...

Benhammouche, Tassadit; Melo, Armindo; Martins, Zita; Faria, Miguel A.; Pinho, Susana C.M.; Ferreira, Isabel M.L.P.V.O.; Zaidi, Farid

The nutritional value and digestibility of leaf proteins is still a major issue. Therefore, the goal of this work was to optimize the production of a protein concentrate (PC) from Moringa Oleifera defatted leaves (MODL) by enzymatic extraction using Viscozyme L and evaluate its nutritional quality and digestibility. Protein extraction conditions were screened using a factorial design. Enzyme/Substrate ratio and...


Bioaccessibility and intestinal uptake of minerals from different types of home...

Faria, Miguel A.; Araújo, Alfredo; Pinto, Edgar; Oliveira, César; Oliva-Teles, MT; Almeida, Agostinho; Delerue-Matos, Cristina

Limited information exists on the bioaccessibility and intestinal uptake of essential minerals from different types of beans cooked through different cooking methods. This study aimed to estimate the in vitro bioaccessibility and intestinal uptake of the essential minerals K, Ca, Mg, Fe, Zn, Mn, Cu and Mo from four different types of beans (kidney, black, white and cowpea) cooked under different conditions (hom...


Modeling of α-acids and xanthohumol extraction in dry-hopped beers

Machado, Júlio C.; Faria, Miguel A.; Melo, Armindo; Martins, Zita E.; Ferreira, Isabel M.P.L.V.O.

The practice of dry-hopping has been used by the brewing industry to obtain beers with increased contents of flavor and bitterness compounds. Notwithstanding this, other compounds such as α-acids (AA) and xhanthohumol (XN) are co-extracted influencing the final characteristics of the beer, particularly its beneficial bioactivity. In this context a model for the understanding of AA and XN extraction by dry-hoppi...


A novel small-caliber bacterial cellulose vascular prosthesis: production, char...

Leitão, Alexandre F.; Faria, Miguel A.; Faustino, Augusto M. R.; Moreira, Ricardo; Mela, Petra; Loureiro, Luís; Silva, Ivone; Gama, F. M.

Vascular grafts are used to bypass damaged or diseased blood vessels. Bacterial cellulose (BC) has been studied for use as an off-the-shelf graft. Herein, we present a novel, cost-effective, method for the production of small caliber BC grafts with minimal processing or requirements. The morphology of the graft wall produced a tensile strength above that of native vessels, performing similarly to the current co...


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