2 documents found, page 1 of 1
Personalized bacteriophage therapy outcomes for 100 consecutive cases: a multic...
Pirnay, Jean-Paul; Djebara, Sarah; Steurs, Griet; Griselain, Johann; Cochez, Christel; De Soir, Steven; Glonti, Tea; Spiessens, An; Vanden Berghe, EmilyIn contrast to the many reports of successful real-world cases of personalized bacteriophage therapy (BT), randomized controlled trials of non-personalized bacteriophage products have not produced the expected results. Here we present the outcomes of a retrospective observational analysis of the first 100 consecutive cases of personalized BT of difficult-to-treat infections facilitated by a Belgian consortium i...
Genome sequence of the broad host range salmonella bacteriophage phi PVP-SE1
Santos, Sílvio Roberto Branco; Kropinski, Andrew M.; Villegas, André; Krylov, Victor; Carvalho, Carla M.; Ferreira, Eugénio C.; Azeredo, JoanaSalmonella is an important zoonotic pathogen and remains the primary cause of reported food poisoning worldwide with massive outbreaks. The increased resistance of Salmonella to antibiotics and other biocides has encouraged the development of alternatives to chemotherapy such as phage therapy. Phage phi PVP-SE1 is a salmonella phage isolated from a Germany (Regensburg) wastewater plant. This phage is characteri...