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Effect of folic acid in a modified experimental model of anorectal malformation...

Faria,Danilo José Fiorindo; Simões,Manuel de Jesus; Teixeira,Luciana Cristina; Faria,Angela Tucci Pinheiro; Cintra,Álvaro Edmundo Simões Ulhoa

PURPOSE: To determine the effect of a single dose of adriamycin (ADR) to induce anorectal malformations (ARMs) and determine the effect of folic acid (FA) in this model. METHODS: Ten female Wistar rats were divided randomly in two groups. Group A - ADR; Group B - FA+ADR. Dams from group B received daily, since two weeks before the pregnancy to the end of pregnancy, FA (50mg/kg) by gavage. Dams from both groups ...

Date: 2016   |   Origin: Oasisbr
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