3 documents found, page 1 of 1
Obesity Increases Gene Expression of Markers Associated With Immunosenescence i...
Brunelli, Diego T.; Boldrini, Vinicius O.; Bonfante, Ivan L. P.; Duft, Renata G.; Mateus, Keryma; Costa, Leonardo Santos; Chacon-Mikahil, Mara P. T.Recently, it has been argued that obesity leads to a chronic pro-inflammatory state that can accelerate immunosenescence, predisposing to the early acquisition of an immune risk profile and health problems related to immunity in adulthood. In this sense, the present study aimed to verify, in circulating leukocytes, the gene expression of markers related to early immunosenescence associated with obesity and its ...
Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response throug...
Codo, Ana Campos; Davanzo, Gustavo Gastão; Monteiro, Lauar de Brito; de Souza, Gabriela Fabiano; Muraro, Stéfanie Primon; Virgilio-da-Silva, João VictorMade available in DSpace on 2020-12-12T02:25:21Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-09-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Fundo de Apoio ao Ensino, à Pesquisa e Extensão, Universidade Estadual de Campinas; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); COVID-19 can resul...
Depression and anxiety in patients with multiple sclerosis treated with interfe...
Tauil, Carlos Bernardo; Lima, Amanda D. da Rocha; Ferrari, Breno B.; Silva, Veronica A. G. da; Moraes, Adriel S.; Silva, Flavia M. daDepression/anxiety (D/A) occurs in up to 50% of multiple sclerosis (MS) patients. Proinflammatory cytokines induce classical symptoms of depression. Activation of the inflammatory response also triggers production of indoleamine 2,3-dioxygenase (IDO), which catabolizes tryptophan, the amino acid precursor of serotonin and melatonin. It has been suggested that IDO is the link between the immune and serotonergic ...