BACKGROUND/AIMS: Neurodegeneration with brain iron accumulation (NBIA) type I is a rare disease that can be divided into a classical or atypical variant, according to age of onset and clinical pattern. Neuro-ophthalmological involvement has been documented in the classical variant but only anecdotically in the atypical variant. We sought to describe the visual and ocular motor function in patients with atypical...
PURPOSE: The purpose of this study is to compare the efficacy and safety of intravitreal aflibercept (IVA) with sham photodynamic therapy (sPDT) versus IVA with verteporfin PDT (vPDT) in a Caucasian population with treatment-naive polypoidal choroidal vasculopathy (PCV), enrolling into a treat and extend (T&E) regimen. METHODS AND ANALYSIS: Randomised, double-masked, sham-controlled, multicentre phase 4 investi...
To evaluate long-term results and predictors of efficacy in patients with macular edema due to retinal vein occlusion (RVO) treated with intravitreal ranibizumab in a clinical practice setting.
Objectivo: Descrever um caso da rara síndroma de proliferação melanocítica uveal difusa bilateral(BDUMP). Descrição do Caso Clínico: Doente, do sexo masculino, 64 anos, fumador, com história de Perda progressiva e grave da acuidade visual bilateral nos últimos 9 meses. A observação apresentava melhor acuidade visual corrigida (MAVC) de 20/50 no OD e de 20/70 no OE, catarata bilateral e tumor pigmentado da íris ...