7 documents found, page 1 of 1

Enhanced Visual Attentional Modulation in Patients with Inherited Peripheral Re...

The role of attentional mechanisms in peripheral vision loss remains an outstanding question. Our study was aimed at determining the effect of genetically determined peripheral retinal dystrophy caused by Retinitis Pigmentosa (RP) on visual cortical function and tested the recruitment of attentional mechanisms using functional magnetic resonance imaging (fMRI). We included thirteen patients and twenty-two age- ...

Primary visual cortical remapping in patients with inherited peripheral retinal...

Human studies addressing the long-term effects of peripheral retinal degeneration on visual cortical function and structure are scarce. Here we investigated this question in patients with Retinitis Pigmentosa (RP), a genetic condition leading to peripheral visual degeneration. We acquired functional and anatomical magnetic resonance data from thirteen patients with different levels of visual loss and twenty-two...

Long term cortical plasticity in visual retinotopic areas in humans with silent...

Visual cortical plasticity induced by overt retinal lesions (scotomas) has remained a controversial phenomenon. Here we studied cortical plasticity in a silent model of retinal ganglion cell loss, documented by in vivo optical biopsy using coherence tomography. The cortical impact of non-scotomatous subtle retinal ganglion cell functional and structural loss was investigated in carriers of the mitochondrial DNA...

Retinal function in best macular dystrophy: relationship between electrophysiol...

PURPOSE: To establish structure-function correlations across the visual field, to investigate disease progression in Best macular dystrophy (BMD), by correlating structural damage with retinal function as assessed by the combination of psychophysics and multifocal electrophysiology. METHODS: Spatial achromatic and chromatic contrast sensitivities (probing red-green and blue-yellow pathways) were assessed using ...

Evidence of widespread retinal dysfunction in patients with stargardt disease a...

PURPOSE: To characterize contrast sensitivity (CS) across the visual field for two achromatic spatial-temporal frequencies in 21 families with Stargardt disease (STGD) and to correlate psychophysical impairment with patterns of change in multifocal electroretinography (mfERG). METHODS: Twenty-seven eyes from patients with STGD, 16 eyes from asymptomatic relatives, and 44 age-matched control eyes were included. ...

Visual phenotype in Williams-Beuren syndrome challenges magnocellular theories ...

Breakdown of the Inner and Outer Blood Retinal Barrier in Streptozotocin-Induce...

Using vitreous fluorophotometry and quantitative fluorescence microscopy the authors studied the permeability of the blood-retinal barrier (BRB) to fluorescein in control and in 8 days streptozotocin-induced diabetic rats.; http://www.sciencedirect.com/science/article/B6WFD-45JC7TK-T/1/ad834a7e41da87410003af7710548c3d