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Proteomic landscape of extracellular vesicles for diffuse large b‐cell lymphoma...

Carvalho, Ana Sofia; Baeta, Henrique; Henriques, Andreia F.A.; Ejtehadifar, Mostafa; Tranfield, Erin M.; Sousa, Ana Laura; Farinho, Ana

Funding Information: R.M. is supported by Funda??o para a Ci?ncia e a Tecnologia (CEEC position, 2019?2025 investigator). This article is a result of the projects (iNOVA4Health?UID/Multi/04462/2013), supported by Lisboa Portugal Regional Operational Programme (Lisboa2020), under the PORTUGAL 2020 Partnership Agreement, through the European Regional Development Fund (ERDF). This work is also funded by FEDER fund...


Targeting senescent cells improves functional recovery after spinal cord injury

Paramos-de-Carvalho, Diogo; Martins, Isaura; Cristóvão, Ana Margarida; Dias, Ana Filipa; Neves-Silva, Dalila; Pereira, Telmo; Chapela, Diana

Funding Information: We are grateful to A. Nascimento, A. Temudo, and J. Rino from the Bioimaging Unit for all of their precious advice. We thank the support given by the Fish and Rodent Facilities and the Histology and Comparative Pathology Laboratory, A. Ribeiro and C. de Sena-Tomás for critical reading of the manuscript, and M. Rebocho-da-Costa for help with the graphical abstract. D.P.d.C. was supported by ...


Is the proteome of bronchoalveolar lavage extracellular vesicles a marker of ad...

Carvalho, Ana Sofia; Moraes, Maria Carolina Strano; Na, Chan Hyun; Fierro-Monti, Ivo; Henriques, Andreia; Zahedi, Sara; Bodo, Cristian

Funding: R.M. is supported by Fundação para a Ciência e a Tecnologia (CEEC position, 2019–2025 investigator). This article is a result of the projects (iNOVA4Health—UID/Multi/04462/2013), supported by Lisboa Portugal Regional Operational Programme (Lisboa2020), under the PORTUGAL 2020 Partnership Agreement, through the European Regional Development Fund (ERDF). This work is also funded by FEDER funds through th...


Reconstruction of a 10-mm-long median nerve gap in an ischemic environment usin...

Casal, Diogo; Mota-Silva, Eduarda; Iria, Inês; Alves, Sara; Farinho, Ana; Pen, Cláudia; Lourenço-Silva, Nuno; Mascarenhas-Lemos, Luís

The aim of this study was to evaluate in the Wistar rat the efficacy of various autologous nerve conduits with various forms of blood supply in reconstructing a 10-mm-long gap in the median nerve (MN) under conditions of local ischemia. A 10-mm-long median nerve defect was created in the right arm. A loose silicone tube was placed around the nerve gap zone, in order to simulate a local ischemic environment. Rat...


Control of tissue growth by Yap relies on cell density and F-actin in zebrafish...

Mateus, Rita; Lourenço, Raquel; Fang, Y.; Brito, G; Farinho, Ana; Valerio, Fabio; Jacinto, Antonio

This work was supported by funding from Fundacao para a Ciencia e Tecnologia [SFRH/BD/62126/2009, PTDC/BEX-BID/1176/2012]; and Agence Nationale de la Recherche [ANR-11-BSV5-0021].; Caudal fin regeneration is characterized by a proliferation boost in the mesenchymal blastema that is controlled precisely in time and space. This allows a gradual and robust restoration of original fin size. However, how this is est...


Denervation impairs regeneration of amputated zebrafish fins

Simões, Mariana G.; Bensimon-Brito, Anabela; Fonseca, Mariana; Farinho, Ana; Valério, F.; Afonso, Nuno; Kumar, A.; Jacinto, Antonio

info:eu-repo/grantAgreement/FCT/3599-PPCDT/126111/PT We thank to the IMM Fish Facility manager Lara Carvalho for support with fish care, to the CEDOC Fish Facility, to the IMM Bioimaging Unit and to the IGC Unit of Imaging and Cytometry. We thank to Leonor Saude, Henry Roehl and Kenneth Poss for providing probes. We thank Jeremy Brockes, Jacqueline Geraudie, Rita Fior, Elsa Abranches, Joaquin Rodriguez Leon, Nu...


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