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Neoplastic and pre-neoplastic lesions of the oesophagus and gastro-oesophageal ...

Grillo, F; Mastracci, L; Saragoni, L; Vanoli, A; Limarzi, F; Gullo, I; Ferro, J; Paudice, M; Parente, P; Fassan, M

Oesophageal and gastro-oesophageal junction (GOJ) neoplasms, and their predisposing conditions, may be encountered by the practicing pathologist both as biopsy samples and as surgical specimens in daily practice. Changes in incidence of oesophageal squamous cell carcinomas (such as a decrease in western countries) and in oesophageal and GOJ adenocarcinomas (such as a sharp increase in western countries) are bei...


Precancerous lesions of the stomach, gastric cancer and hereditary gastric canc...

Gullo, I; Grillo, F; Mastracci, L; Vanoli, A; Carneiro, F; Saragoni, L; Limarzi, F; Ferro, J; Parente, P; Fassan, M

Gastric cancer accounts for about 6% of cancers worldwide, being the fifth most frequently diagnosed malignancy and the third leading cause of cancer related death. Gastric carcinogenesis is a multistep and multifactorial process and is the result of the complex interplay between genetic susceptibility and environmental factors. The identification of predisposing conditions and of precancerous lesions is the ba...


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