51 documents found, page 1 of 6
Magneto-plasmonic bionanocomposites for on-site SERS detection of water contami...
Soares, Sofia F.; Silva, Nuno M. A. S.; Brenheiro, João; Fateixa, Sara; Daniel-da-Silva, Ana L.; Trindade, TitoMagneto-plasmonic nanosystems have emerged as important multifunctional structures for several sensing applications, including on-site water quality monitoring. In this scenario, these nanosystems can integrate magnetic assisted separation procedures associated with optical detection of water contaminants, by exploring the surface-enhanced Raman scattering effect (SERS). Among the several modalities proposed fo...
Integrated magneto-plasmonic nanostructures-based immunoassay for galectin-3 de...
Fateixa, Sara; Martins, Ana L. F.; Colaço, Beatriz; António, Maria; Daniel-da-Silva, Ana L.Cardiovascular diseases remain a leading cause of global mortality, highlighting the need for accurate diagnostic tools and the detection of specific cardiac biomarkers. Surface-enhanced Raman scattering (SERS) spectroscopy has proved to be a promising alternative diagnostic tool to detect relevant biomarkers compared to traditional methods. To our knowledge, SERS methodology has never been used to detect galec...
Silk sericin/chitosan supramolecular multilayered thin films as sustainable cyt...
Rosas, Miguel; Sousa, Cristiana F. V.; Pereira, Ana; Amaral, Adérito J. R.; Pesqueira, Tamagno; Patrício, Sónia G.; Fateixa, SaraSilk sericin (SS) has been widely discarded as a waste by the silk textile industry during the degumming process to obtain fibroin. However, in the past decade, an in-depth understanding of its properties and functions turned it into a high added-value biomaterial for biomedical applications. Herein, we report the molecular design and development of sustainable supramolecular multilayered nanobiomaterials encom...
Surface-enhanced Raman scattering detection of thiram and ciprofloxacin using c...
Martins, Natércia C. T.; Fateixa, Sara; Nogueira, Helena I. S.; Trindade, TitoFast detection of contaminants of emerging concern (CECs) in water resources is of great environmental interest. Ideally, sustainable materials should be used in water quality monitoring technologies implemented for such purposes. In this regard, the application of bio-based materials aimed at the fabrication of analytical platforms has become of great importance. This research merges both endeavors by explorin...
Raman imaging studies on the stability of Paracetamol tablets under different s...
Fateixa, Sara; Mulandeza, Otílio; Nogueira, Helena I. S.; Trindade, TitoThe applicability of Raman imaging for pharmaceutics production ranges from the characterization of pharmaceutical formulations, kinetic processes in drug delivery to the rapid detection and identification of counterfeit drugs/contaminants. Acetaminophen (Paracetamol, APAP) is an analgesic and antipyretic drug and one of the most consumed medicines worldwide. On the other hand, the compound 4-aminophenol (4-AP)...
Arrays of graphene-quantum dots-supported DNA oligonucleotides as self-indicati...
Monteiro, Ana R.; Ramos, Catarina I. V.; Fateixa, Sara; Neves, Maria G. P. M. S.; Trindade, TitoThe functionalization of deoxyribonucleic acid (DNA) with nanomaterials is a promising strategy to optimize the loading and efficiency of drugs in targeted clinical therapies. Herein we report a novel approach to construct arrays comprising blue- (B) or aqua green- (AG) emitting ethylenediamine-modified graphene quantum dots (GQDs) and DNA oligonucleotides that are able to fold into different structures, namely...
Additive manufacturing-enabled architected nanocomposite lattices coated with p...
Fateixa, Sara; Landauer, Marc; Schneider, Johannes; Kumar, Shanmugam; Böhm, RobertNovel low-cost materials to uptake and detect vestigial amounts of pesticides are highly desirable for water quality monitoring. Herein, are demonstrated, for the first time, surface-enhanced Raman scattering (SERS) sensors enabled via additively manufactured lattices coated with plasmonic nanoparticles (NPs) for detecting pesticides in real water samples. The architected lattices comprising polypropylene (PP) ...
Interfacial assembly of zinc(II) phthalocyanines on graphene oxide (GO): stable...
Monteiro, Ana R.; Ramos, Catarina I. V.; Lourenço, Leandro M. O.; Fateixa, Sara; Rodrigues, Joana catarina; Neves, Maria G. P. M. S.; Trindade, TitoHypothesis The aggregation of phthalocyanines (Pcs) enfeebles their suitability as G-quadruplex (G4) ligands over time. It is hypothesized that the interfacial assembly of Pcs on graphene oxide (GO) influences intermolecular interactions, thereby affecting their physicochemical properties and inducing stabilization of Pcs in solution. Hence, the stacking of Pcs on GO could be tuned to create nanosystems with th...
Carbamazepine polymorphism: a re-visitation using Raman imaging
Fateixa, Sara; Nogueira, Helena I. S.; Trindade, TitoRaman imaging methods have appeared in the last years as a powerful approach to monitoring the quality of pharmaceutical compounds. Because polymorphism occurs in many crystalline pharmaceutical compounds, it is essential to monitor polymorphic transformations induced by different external stimulus, such as temperature changes, to which those compounds may be submitted. Raman imaging with k-means cluster analys...
Colloidal nanomaterials for water quality improvement and monitoring
Estrada, Ana C.; Daniel-da-Silva, Ana L.; Leal, Cátia; Monteiro, Cátia; Lopes, Cláudia B.; Nogueira, Helena I. S.; Lopes, Isabel; Martins, Maria J.Water is the most important resource for all kind forms of live. It is a vital resource distributed unequally across different regions of the globe, with populations already living with water scarcity, a situation that is spreading due to the impact of climate change. The reversal of this tendency and the mitigation of its disastrous consequences is a global challenge posed to Humanity, with the scientific comm...