20 documents found, page 1 of 2
O rato fêmea como modelo de cancro da mama: passado, presente e futuro
Faustino-Rocha, AnaO presente documento intitulado Sumário da lição “O rato fêmea como modelo de cancro da mama: passado, presente e futuro” é apresentado para avaliação em provas de agregação na área disciplinar de Ciências Veterinárias, da Universidade de Évora, com vista à atribuição do título de Agregado, em conformidade com o Decreto-Lei nº 239/2007, de 19 de junho (1ª série, nº 116). Esta lição encontra-se alinhada com o re...
Osteologia e miologia: membro torácico
Faustino-Rocha, Ana; Lança, Maria JoãoOSTEOLOGIA E MIOLOGIA:MEMBRO TORÁCICO
Exposure to ultraviolet B radiation or oral supplementation with vitamin D and ...
Franco, F; Patrício, R; Faustino-Rocha, AnaA vitamina D é responsável pela regulação de várias funções, como a homeostase do cálcio. Vários estudos têm pretendido compreender as necessidades de vitamina D de cada espécie, e a sua aquisição na natureza. O presente estudo teve como objetivo abordar a influência da suplementação com vitamina D e cálcio, ou exposição à radiação ultravioleta (UV) sobre os níveis de cálcio ionizado em Eublepharis macularius (...
The role of natural compounds in rat mammary cancer: the beneficial effects of ...
Azevedo, Tiago; Silva, Jessica; Peixoto, Francisco P.; Silvestre-Ferreira, Ana C.; Gama, Adelina; Seixas, Fernanda; Finimundy, Tiane C.; Barros, LillianBreast cancer is the most diagnosed cancer among women, and a leading cause of death worldwide. Santolina chamaecyparissus L. is a plant with multiple health benefits, including anticancer and anti-diabetic properties. This study aimed to assess the chemopreventive effects of S. chamaecyparissus aqueous extract (SCE) in an animal model of mammary cancer. A total of 28 four-week-old female Wistar rats were divid...
Interplay Between Western Diet and Mammary Cancer: Data from a Chemically-induc...
Silva, Jessica; Aires, Inês; Peixoto, Francisco P.; Neuparth, Maria João; Queiroga, Felisbina; Seixas, Fernanda; Ferreira, Rita; Faustino-Rocha, AnaThis study aimed to investigate the influence of Western diet on mammary cancer in Wistar female rats, focusing on systemic responses and tumor development. Materials and Methods: Twenty-eight Wistar female rats were acclimatized and divided into four experimental groups (n=7 each): Western diet (WD), Western diet with N-methyl-N-nitrosourea (MNU) administration (WD+MNU), standard diet (CTR), and standard diet ...
Aloysia citrodora extract as a chemopreventive agent against HPV16-induced lesi...
Medeiros-Fonseca, Beatriz; Faustino-Rocha, Ana; Silva, Jessica; Silva, Mónica; Pires, Maria João; Neuparth, Maria João; Vala, HelenaAloysia citrodora has a long history of traditional use in treating various ailments. This study evaluated the in vivo chemopreventive efficacy and systemic toxicity of an extract of A. citrodora in a transgenic mouse model of HPV16 (human papillomavirus type 16)-induced cancer. Methods: The experiment involved six groups (n = 5): group 1 (G1, wild-type (WT), water), group 2 (G2, HPV, water), group 3 (G3, WT, 0...
Realistic Aspects of Cardiac Ultrasound in Rats: Practical Tips for Improved Ex...
Silva, Jessica; Ginja, Mário; Oliveira, Paula A.; Duarte, José Alberto; Faustino-Rocha, AnaEchocardiography is a reliable and non-invasive method for assessing cardiac structure and function in both clinical and experimental settings, offering valuable insights into disease progression and treatment efficacy. The successful application of echocardiography in murine models of disease has enabled the evaluation of disease severity, drug testing, and continuous monitoring of cardiac function in these an...
Exploring the therapeutic potential of Quercus ilex acorn extract in papillomav...
Medeiros-Fonseca, Beatriz; Faustino-Rocha, Ana; Pires, Maria João; Neuparth, Maria João; Vala, Helena; Vasconcelos-Nóbrega, Cármen; Gouvinhas, IrenePapillomaviruses (PVs) infections have been documented in numerous animal species across different regions worldwide. They often exert significant impacts on animal health and livestock production. Scientists have studied natural products for over half a century due to their diverse chemical composition, acknowledging their value in fighting cancer. Acorns (Quercus ilex) are believed to have several unexplored ...
Addressing new therapeutic strategies using models
Faustino-Rocha, Ana; Oliveira, Paula AA disease model displays pathological processes observed in human or animal diseases. The models are fundamental tools in biomedical research, and they are invaluable for providing new insights into mechanisms underlying organ function, establishing the pathophysiology of a disease, and testing potential therapeutic approaches.Models have been long used to study several diseases, including cardiovascular, oncol...
Prostate cancer.
Faustino-Rocha, Ana; Oliveira, Paula A.The prostate is the largest accessory gland of the male reproductive tract. Together with seminal vesicles and bulbourethral glands, the prostate is responsible for the production of an alkaline fluid that forms part of the seminal fluid. The prostates of men over 40 years of age are commonly affected by several pathologies, such as benign prostate hyperplasia and cancer. Prostate cancer is one of the most freq...