79 documents found, page 1 of 8
A utilização de modelos no ensino da Anatomia Veterinária: passado, presente e ...
Martinho, C; Ferradeira, C; Catita, J; Faustino-Rocha, Ana IAs abelhas são os polinizadores mais importantes do mundo. As ameaças à saúde das abelhas continuam a aumentar a nível mundial, contribuindo para a diminuição da sua produtividade. As abelhas são suscetíveis a uma enorme variedade de agentes patogénicos, incluindo vírus, bactérias, fungos, protozoários e ácaros. Este trabalho teve como objetivo apresentar uma compilação das principais doenças parasitárias, bact...
Hepatocellular Early Apoptosis Associated with HES 130/0.4 Administration for V...
Vala, Helena; Faustino-Rocha, Ana I; Curz, Rita; Venâncio, Carlos; Silva, Aura; Mesquita, João R; Ortiz, Ana L; Ferreira, David AHydroxyethyl starch 130/0.4 is a colloid solution used for expanding the plasma volume in situations of severe hypotension that, for example, may result from acute severe blood loss. This volume expansion allows for a more adequate organ perfusion, and consequent oxygen and nutrient delivery to the tissues. Nevertheless, several secondary effects associated with the hydroxyethyl starch 130/0.4 administration ha...
loysia citrodora extract as a chemopreventive agent against HPV16-induced lesio...
Medeiros-Fonseca, Beatriz; Faustino-Rocha, Ana I; Silva, Jessica; Pires, Maria João; Neuparth, Maria João; Vala, Helena; Vasconcelos-Nóbrega, CarmenAim: Aloysia citrodora has a long history of traditional use in treating various ailments. This study evaluated the in vivo chemopreventive efficacy and systemic toxicity of an extract of A. citrodora in a transgenic mouse model of HPV16 (human papillomavirus type 16)-induced cancer. Methods: The experiment involved six groups (n = 5): group 1 (G1, wild-type (WT), water), group 2 (G2, HPV, water), group 3 (G3, ...
Relation between infrared thermometry and thermal imaging for assessment of rod...
Oliveira, Paula A.; Gonçalves, Lio; Gonçalves, Mariana; Venâncio, Carlos; Azevedo, Tiago; Ribeiro, Carla; Reis, Rita; Faustino-Rocha, Ana IAnimals have been used for biomedical research since ancient times. Humane endpoints have been increasingly implemented during experimental protocols to prevent or alleviate animals’ suffering. Body temperature is an indicator of stress or anxiety. Infrared thermometer (IRT) and infrared thermal imaging camera (TIC) are commercially available for temperature measurement. This study aimed to determine mice and r...
The veterinary medicinal products supply gap: a practical insight based on the ...
Nogueira, Rafaela; Jota Baptista, Catarina; Gonçalves, Elisabete; Coelho, Ana Cláudia; Faustino-Rocha, Ana I; Purriños, MR; Gonzalo-Orden, JMThe Regulation (EU) 2019/6 establishes that the veterinary prescriptions should follow a cascade, according to their availability of the market. In sum, the veterinarian is authorized to use a medicine for human use only if there is no product available for the same or other therapeutic indication, in the same or another animal species. This study aims to analyse the application of Regulation (EU) 2019/6 in the...
Contribution of non-steroidal anti-inflammatory drugs to breast cancer treatmen...
Ferreira, Tiago; Faustino-Rocha, Ana I; Gaspar, VM; Medeiros, Rui; Mano, JF; Oliveira, Paula A.Chronic inflammation plays a crucial role in carcinogenesis. High levels of serum prostaglandin E2 and tissue overexpression of cyclooxygenase-2 (COX-2) have been described in breast, urinary, colorectal, prostate, and lung cancers as being involved in tumor initiation, promotion, progression, angiogenesis, and immunosuppression. Non-steroidal anti-inflammatory drugs (NSAIDs) are prescribed for several medical ...
The lifestyle of the leopard gecko and the importance of ultraviolet radiation,...
Franco, F; Oliveira, Paula A; Patrício, Rui; Faustino-Rocha, Ana IThe gecko leopard (Eublepharis macularius) was first described in 1854 by British herpetol- ogist Edward Blyth. It is one of the most pop- ular pet lizard species, due to its docile tem- perament, ease of maintenance and reproduc- tion in captivity, its high longevity and small size, and its beauty and diversity of colours and patterns. Ultraviolet (UV) radiation is an important behavioural regulator. Vitamin D...
. A spontaneous ovarian teratoma in a FVB/n female mouse: case report and liter...
Oliveira, Paula A.; Faustino-Rocha, Ana I; Gil da Costa, RM; Nascimento-Gonçalves, E; Calado, AM; Jota Baptista, C; Gama, A; Seixas, FBackground: Teratomas are rare types of germ cell neoplasms composed of various differentiated or undifferentiated tissues. Case Description: A 25-week-old female control FVB /n mouse in a 4-week toxicity study presented abdominal distension and poor body condition. It was euthanized, and the necropsy examination revealed a large mass connected to the tip of the right uterine horn, occupying the entire abdomina...
Quercus spp. extract as a promising preventive or therapeutic strategy for canc...
Oliveira, Paula A.; Vasconcelos-Nóbrega, C; Pires, MJ; Vala, H; Barros, AIRNA; Faustino-Rocha, Ana IAcorns have traditionally been used in the human diet and for the treatment of specific diseases. Therefore, the present study performed a systematic review of studies which investigated the effects of Quercus spp. extracts in cancer prevention and treatment. A systematic literature search was performed for original records which addressed the anticancer effects of Quercus spp. extract in in vitro and in vivo c...
Evolution of models of prostate cancer: its contribution to current therapies
Faustino-Rocha, Ana I; Jota-Baptista, C; Gonçalves, E; Oliveira, Paula A.Prostate cancer (PCa) is among the most frequent cancers worldwide. Nowadays, several therapeutic strategies are available for PCa treatment, namely chemotherapy, immunotherapy, radiotherapy, and hormonal therapy. Despite existing therapeutic approaches, in vitro and in vivo models are essential to better understand cancer development and search for more effective therapies, with a positive impact in cancer pat...