1 document found, page 1 of 1

Sort by Issue Date

The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in...

de Oliveira, Rita Machado; Vicente Miranda, Hugo; Francelle, Laetitia; Pinho, Raquel; Szegö, Éva M.; Martinho, Renato; Munari, Francesca

Sirtuin genes have been associated with aging and are known to affect multiple cellular pathways. Sirtuin 2 was previously shown to modulate proteotoxicity associated with age-associated neurodegenerative disorders such as Alzheimer and Parkinson disease (PD). However, the precise molecular mechanisms involved remain unclear. Here, we provide mechanistic insight into the interplay between sirtuin 2 and α-synucl...


1 Results

Queried text

Refine Results

Author





















Date


Document Type


Access rights


Resource


Subject