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Dose-response evaluation of a copaiba-containing varnish against streptococcus ...

Valadas, Lídia Audrey Rocha; Gurgel, Mariana Fernandes; Mororó, Joelma Martins Mororó; Fonseca, Said Gonçalves da Cruz; Fonteles, Cristiane Sá Roriz

Introduction: Dental caries is the most prevalent disease in humans and its incidence is particularly high during childhood. The use of medicinal plants is a common practice in Brazil. Objective: To evaluate the optimal antimicrobial concentration of Copaifera langsdorffii (copaiba) oil-resin, in the form of dental varnish, against Streptococcus mutans (S. mutans) in children. Methods: Twenty-four children, car...

Date: 2020   |   Origin: Oasisbr

Innovative treatment using tilapia skin as a xenograftfor partial thickness bur...

Lima-Junior, Edmar Maciel; Moraes Filho, Manoel Odorico de; Costa, Bruno Almeida; Fechine, Francisco Vagnaldo; Moraes, Maria Elisabete Amaral de

Tilapia skin has non-infectious microbiota, high amounts of type I collagen, and similar morphological structure to human skin, so it has been suggested as a potential xenograft for the management of burn wounds. A 23-year-old male patient, with no comorbidities, arrived at our burn treatment center after a thermal injury caused by contact with flames from a gunpowder explosion. Superficial partial thickness bu...

Date: 2019   |   Origin: Oasisbr

Prevalência de hipertensão arterial e fatores de risco entre pessoas com síndro...

Cunha, Gilmara Holanda da; Lima, Maria Amanda Correia; Galvão, Marli Teresinha Gimeniz; Fechine, Francisco Vagnaldo; Fontenele, Marina Soares Monteiro

Objectives: to verify the prevalence of arterial hypertension and its risk factors among people with acquired immunodeficiency syndrome under antiretroviral therapy. Method: crosssectional study with 208 patients. Data collection was conducted through interviews using a form containing data on sociodemographic, clinical and epidemiological aspects, hypertension risk factors, blood pressure, weight, height, body...

Date: 2019   |   Origin: Oasisbr

Resíduos de insulinoterapia produzidos no domicílio de diabéticos acompanhados ...

Cunha, Gilmara Holanda da; Barbosa, Raiza Verônica Almeida; Fontenele, Marina Soares Monteiro; Lima, Maria Amanda Correia; Franco, Katia Barbosa

Objective: To analyze the insulin therapy waste disposal produced in the households of people with diabetes mellitus (DM). Method: Cross-sectional study with 105 Primary Care patients. Socio-demographic and clinical variables and insulin therapy practice were analyzed through the absolute and relative frequencies, Fisher’s exact test and prevalence ratio (PR). Results: The association between types of insulin (...

Date: 2018   |   Origin: Oasisbr

α-Lipoic acid as adjunctive treatment for schizophrenia : an open-label trial

Sanders, Lia Lira Olivier; Menezes, Carlos Eduardo de Souza; Chaves Filho, Adriano José Maia; Viana, Glautemberg de Almeida; Fechine, Francisco Vagnaldo

Purpose/Background: Accumulating evidence suggests an involvement of oxidative stress in the pathophysiology of schizophrenia. This offers a hypothesis-derived therapeutic approach to hinder oxidative damage and its clinical sequelae. α-Lipoic acid (ALA) is a powerful natural antioxidant indicated to treat diabetic neuropathy. Methods/Procedures: In this pilot investigation, we administered ALA (100 mg/d) for 4...

Date: 2018   |   Origin: Oasisbr

Effect of treatment with sitagliptin on somatosensory-evoked potentials and met...

Barros, Joelma Ines Tagliapietra; Fechine, Francisco Vagnaldo; Montenegro Júnior, Renan Magalhães; Vale, Otoni Cardoso do; Fernandes, Virgínia Oliveira

Objective: To evaluate the effect of sitagliptin on somatosensory-evoked potentials (SEPs) and metabolic control in patients with type 2 diabetes mellitus without clinical diabetic neuropathy. Materials and methods: Interventional, prospective, and open study. Patients with less than six months from the diagnosis were included. Examinations of SEPs and laboratory tests at fasting and after food stimulation were...

Date: 2014   |   Origin: Oasisbr

Effect of a combination of medium chain triglycerides, linoleic acid, soy lecit...

Magalhães, Maria Sonia Felício; Fechine, Francisco Vagnaldo; Macedo, Rafael Nogueira de; Monteiro, Diego Levi Silveira; Oliveira, Cecília Carvalho

Purpose: The aim of the study was to determine the effect of a combination of medium chain triglycerides (caprylic, capric, caproic and lauric acids), linoleic acid (essential fatty acid), vitamins A and E and soy lecithin, through a morphometric study, on the wound healing kinetics of experimental cutaneous ulcers. Methods: A total of 45 male Wistar rats were used, in which a skin flap of total thickness with ...

Date: 2013   |   Origin: Oasisbr

Toxicology and safety of the tincture of Operculina alata in patients with func...

Santos, Luciana Kelly Ximenes dos; Cunha, Gilmara Holanda da; Fechine, Francisco Vagnaldo; Pontes, Andréa Vieira; Oliveira, Jonaina Costa de

The tincture of Operculina alata, popularly known as "tincture of jalapa", is used in Northeast Brazil to treat constipation and encephalic vascular accident, but it has not yet been adequately tested for safety and efficacy. The aim of this study was to evaluate the toxicology and safety of the tincture of O. alata in patients with functional constipation. This was a double-blind, randomized, placebo-controlle...

Date: 2012   |   Origin: Oasisbr

Efficacy and safety of cumaru syrup as complementary therapy in mild persistent...

Carvalho, Elisete Mendes; Cunha, Gilmara Holanda da; Fechine, Francisco Vagnaldo; Uchôa, Célia Regina Amaral; Moraes Filho, Manoel Odorico de

Amburana cearensis is a medicinal plant known as "cumaru". It is used in Northeast Brazil in the treatment of respiratory diseases. This was a randomized, double-blind, placebo-controlled study, with the aim of evaluating the efficacy and safety of cumaru syrup as complementary therapy in mild persistent asthma. The study consisted of 3 phases, pre-treatment, treatment and post-treatment. The primary efficacy o...

Date: 2012   |   Origin: Oasisbr

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