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Organic effects of associating paclitaxel with a lipid-based nanoparticle syste...

Feio, Danielle Cristinne Azevedo; Oliveira, Nayara Cristina Lima de; Pereira, Edmundo Luis Rodrigues; Morikawa, Aleksandra Tiemi

Lipid-based nanoparticle systems have been used as vehicles for chemotherapeutic agents in experimental cancer treatments. Those systems have generally been credited with attenuating the severe toxicity of chemotherapeutic agents. This study aimed to investigate the effects of associating paclitaxel (PTX) with a lipid-based nanoparticle system on a nonhuman primate, Cebus apella, documenting the toxicity as mea...

Date: 2017   |   Origin: Oasisbr
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