2 documents found, page 1 of 1
Recent advances in fluorescent theranostics for Alzheimer's disease: a comprehe...
Francisco, Telmo N.; Malafaia, Daniela; Melo, Lúcia; Silva, Artur M. S.; Albuquerque, Hélio M. T.Alzheimer's disease (AD) is the most common form of neurodegenerative dementia that is rapidly becoming a major health problem, especially in developed countries because of their increasing life expectancy. Two main problems are often associated with the disease: (i) the absence of a widely accessible "gold-standard" for early diagnosis and (ii) lack of effective therapies with disease-modifying effects. The re...
2,2’-[(1E,1’E)-{[Hexa-2,4-diyne-1,6-diylbis(oxy)]bis(2,1-phenylene)}bis(ethene-...
Malafaia, Daniela; Sousa, Joana L. C.; Silva, Artur M. S.; Albuquerque, Hélio M. T.2-Styrylchromones (2-SCs) are interesting compounds for their biological properties as well as versatility as starting materials for further transformations. Herein, we disclose a new 2-SC derivative—2,2’-[(1E,1’E)-{[hexa-2,4-diyne-1,6-diylbis(oxy)]bis(2,1-phenylene)}bis(ethene-2,1- diyl)]bis(4H-chromen-4-one)—which is a dimeric compound formed by two units of 2-SC linked through a 1,3-diyne moiety. It was obta...