4 documents found, page 1 of 1
Chikungunya virus strains from each genetic clade bind sulfated glycosaminoglyc...
McAllister, Nicole; Liu, Yan; Silva, Lisete M.; Lentscher, Anthony J.; Chai, Wengang; Wu, Nian; Griswold, Kira A.; Raghunathan, Krishnan; Vang, LoChikungunya virus (CHIKV) is an arthritogenic alphavirus that causes debilitating musculoskeletal disease. CHIKV displays broad cell, tissue, and species tropism, which may correlate with the attachment factors and entry receptors used by the virus. Cell-surface glycosaminoglycans (GAGs) have been identified as CHIKV attachment factors. However, the specific types of GAGs and potentially other glycans to which ...
Helicobacter pylori lipopolysaccharide structural domains and their recognition...
Silva, Lisete M.; Correia, Viviana G.; Moreira, Ana S.P.; Domingues, Maria Rosário M.; Ferreira, Rui M.; Figueiredo, Céu; Azevedo, Nuno F.The structural diversity of the lipopolysaccharides (LPSs) from Helicobacter pylori poses a challenge to establish accurate and strain-specific structure-function relationships in interactions with the host. Here, LPS structural domains from five clinical isolates were obtained and compared with the reference strain 26695. This was achieved combining information from structural analysis (GC-MS and ESI-MSn) with...
Recognition of DHN-melanin by a C-type lectin receptor is required for immunity...
Stappers, Mark H.T.; Clark, Alexandra E.; Aimanianda, Vishukumar; Bidula, Stefan; Reid, Delyth M.; Asamaphan, Patawee; Hardison, Sarah E.Resistance to infection is critically dependent on the ability of pattern recognition receptors to recognize microbial invasion and induce protective immune responses. One such family of receptors are the C-type lectins, which are central to antifungal immunity. These receptors activate key effector mechanisms upon recognition of conserved fungal cell-wall carbohydrates. However, several other immunologically a...
Recognition of DHN-melanin by a C-type lectin receptor is required for immunity...
Stappers, Mark H. T.; Clark, Alexandra E.; Aimanianda, Vishukumar; Bidula, Stefan; Reid, Delyth M.; Asamaphan, Patawee; Hardison, Sarah E.Resistance to infection is critically dependent on the ability of pattern recognition receptors to recognize microbial invasion and induce protective immune responses. One such family of receptors are the C-type lectins, which are central to antifungal immunity. These receptors activate key effector mechanisms upon recognition of conserved fungal cell-wall carbohydrates. However, several other immunologically a...