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Development of ELISAs for diagnosis of acute typhoid fever in Nigerian children

Felgner, Jiin; Jain, Aarti; Nakajima, Rie; Liang, Li; Jasinskas, Algis; Gotuzzo, Eduardo; Vinetz, Joseph M.; Miyajima, Fabio; Pirmohamed, Munir

Improved serodiagnostic tests for typhoid fever (TF) are needed for surveillance, to facilitate patient management, curb antibiotic resistance, and inform public health programs. To address this need, IgA, IgM and IgG ELISAs using Salmonella enterica serovar Typhi (S. Typhi) lipopolysaccharide (LPS) and hemolysin E (t1477) protein were conducted on 86 Nigerian pediatric TF and 29 non-typhoidal Salmonella (NTS) ...

Date: 2018   |   Origin: Oasisbr

Antibody profiling in patients with mild and severe leptospirosis: a genome-wid...

Aquino, Carolina Lessa; Lindow, Janet C.; Randall, Arlo; Wunder Junior, Elsio Augusto; Pablo, Jozelyn; Nakajima, Rie; Jasinskas, Algis

Fiocruz. Brazilian Ministry of Health. Bio-Manguinhos. Rio de Janeiro, RJ, Brasil; Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Yale School of Public Health. Department of Epidemiology of Microbial Diseases. New Haven, USA; Antigen Discovery Inc. Irvine, CA; Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Yale School of Public Health. Departme...

Date: 2017   |   Origin: Oasisbr

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