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Lectin isolated from Brazilian seeds of velvet bean ( Mucuna pruriens (L) DC.) ...

Lacerda, Rodrigo Rodrigues e; Moreira, Italo Cordeiro; Nascimento, Jader Sabino Jacó do; Lacerda, Ana Carenina Sampaio de; Cabral, Natasha Lucena

Lectins are proteins present in all living beings capable of interacting specifically and reversibly to carbohydrates or glycoconjugates form. They stand out in this family of lectins legumes, which are of special scientific interest because they have differen t biological functions. This study investigated the presence of a lectin in Brazilian seeds of Mucuna , proceeding with their isolation and evaluation of...

Date: 2016   |   Origin: Oasisbr

Evaluation of the modulatory and antibacterial activity of the ethanolic extrac...

Fernandes, Cicera Norma; Sousa, Heloisa Helena Ferreira; Souza, Celestina Elba Sobral; Guedes, Glaucia Morgana Melo; Figueredo, Fernando Gomes

Medicinal plants have been the subject of research in several countries such as Brazil. The Duguetia furfuracea A. St.-Hil., popularly known as araticum-bravo, ata-brava and ata de lobo, has been used in folk medicine as anti-rheumatic drugs, for the treatment of renal dysfunction, spinal pain and stomach, and against pediculosis. This work aimed to analyze the antibacterial effect of the crude extract and frac...

Date: 2014   |   Origin: Oasisbr

Piperine decreases pilocarpine-induced convulsions by GABAergic mechanisms

Cruz, Giovany Michely Pinto da; Felipe, Cícero Francisco Bezerra; Scorza, Fúlvio Alexandre; Costa, Marta Aline Coelho da; Tavares, Alinne Farias

Piperine, an alkaloid present in the Piper genus, was shown to have an anticonvulsant activity, evaluated by the pilocarpine-induced model, in mice. Pilocarpine (350 mg/kg, i.p.) was administered 30 min after piperine (2.5, 5, 10 and 20 mg/kg, i.p.) which significantly increased latencies to 1st convulsion and to death, and percentage of survivals. These parameters were also increased in the pilocarpine groups ...

Date: 2014   |   Origin: Oasisbr

Estudo dos efeitos comportamentais, neuroquímicos e tóxicos do óleo essencial d...

Felipe, Cícero Francisco Bezerra

Ginger (Zingiber officinale Roscoe) is a plant largely used around the world, not just as a spice, but also for its medicinal properties. The behavioral and neurochemical effects were studied in mice daily administered with the essential oil of Ginger (EOG 25, 50 e 100 mg/Kg, i.p. and p.o.). In the 7th day of treatment, it was assessed the elevated-plus maze (EPM), open field (OF) rota rod (RR), passive avoidan...

Date: 2012   |   Origin: Oasisbr

Estudo dos efeitos comportamentais e neuroquímicos da piplartina, alcamida isol...

Felipe, Cícero Francisco Bezerra

Piper tuberculatum Jacq. (pimenta de macaco) is a Piperaceae widely used in Northeast Brazil as a spicy or remedy. The few studies found in the literature on Piplartine (PIP), an alcamide isolated from the plant, lead us to evaluate its potential behavioral and neurobiochemical effects. The results showed that PIP (50 e 100 mg/Kg, i.p.) increased the number of grooming and rearing of mice in the open field and ...

Date: 2012   |   Origin: Oasisbr

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