2 documents found, page 1 of 1
Smouldering multiple sclerosis: the 'real MS'
Giovannoni, Gavin; Popescu, Veronica; Wuerfel, Jens; Hellwig, Kerstin; Iacobaeus, Ellen; Jensen, Michael B; García-Domínguez, José Manuel; Sousa, LíviaUsing a philosophical approach or deductive reasoning, we challenge the dominant clinico-radiological worldview that defines multiple sclerosis (MS) as a focal inflammatory disease of the central nervous system (CNS). We provide a range of evidence to argue that the 'real MS' is in fact driven primarily by a smouldering pathological disease process. In natural history studies and clinical trials, relapses and f...
Testing a global standard for quantifying species recovery and assessing conser...
Grace, Molly K.; Akçakaya, H. Resit; Bennett, Elizabeth L.; Brooks, Thomas M.; Heath, Anna; Hedges, Simon; Hilton‐Taylor, Craig; Hoffmann, MichaelRecognizing the imperative to evaluate species recovery and conservation impact, in 2012 the International Union for Conservation of Nature (IUCN) called for development of a "Green List of Species" (now the IUCN Green Status of Species). A draft Green Status framework for assessing species' progress toward recovery, published in 2018, proposed 2 separate but interlinked components: a standardized method (i.e.,...