28 documents found, page 1 of 3

Evaluation of the antibiofilm efficacy of the natural iron chelators kojic acid...

Two cinnamic acid derivatives as inhibitors of Pseudomonas aeruginosa las and p...

Introduction: Quorum sensing (QS) is a bacterial communication mechanism that regulates gene expression, playing a crucial role in various physiological processes. Interfering with this signalling pathway is a promising strategy to control bacterial pathogenicity and virulence. Objectives: This study evaluated the potential of two cinnamic acid derivatives, ferulic and sinapic acids, to inhibit the las and pqs ...

Targeting quorum sensing: ferulic and sinapic acids compromise Pseudomonas aeru...

Targeting quorum sensing: ferulic and sinapic acids compromise Pseudomonas aeru...

Unravelling the potential of natural chelating agents in the control of Staphyl...

Iron is essential for the formation, maturation and dispersal of bacterial biofilms, playing a crucial role in the physiological and metabolic functions of bacteria as well as in the regulation of virulence. Limited availability of iron can impair the formation of robust biofilms by altering cellular motility, hydrophobicity and protein composition of the bacterial surface. In this study, the antibiofilm activi...

Efficacy of selected phenolic acids in inhibiting the LasI/LasR and PQS quorum ...

Avaliação do potencial de agentes quelantes naturais no controle de biofilmes d...

Suppression of the Pseudomonas aeruginosa communication pathways by ferulic and...

Efficacy of Novel Quaternary Ammonium and Phosphonium Salts Differing in Cation...

Antibacterial resistance poses a critical public health threat, challenging the prevention and treatment of bacterial infections. The search for innovative antibacterial agents has spurred significant interest in quaternary heteronium salts (QHSs), such as quaternary ammonium and phosphonium compounds as potential candidates. In this study, a library of 49 structurally related QHSs was synthesized, varying the ...

Dual action of benzaldehydes: Inhibiting quorum sensing and enhancing antibioti...

Quorum sensing (QS) has a central role in biofilm lifestyle and antimicrobial resistance, and disrupting these signaling pathways is a promising strategy to control bacterial pathogenicity and virulence. In this study, the efficacy of three structurally related benzaldehydes (4-hydroxybenzaldehyde, 4-hydroxy-3-methoxybenzaldehyde (vanillin) and 4-hydroxy-3,5-dimethoxybenzaldehyde (syringaldehyde)) in disrupting...