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Glycans as Key Checkpoints of T Cell Activity and Function

Pereira, M.; Alves, I.; Vicente, M.; Campar, A.; Silva, M.; Padrão, N.; Pinto, V.; Fernandes, Â.; Dias, A.; Pinho, S.

The immune system is highly controlled and fine-tuned by glycosylation, through the addition of a diversity of carbohydrates structures (glycans) to virtually all immune cell receptors. Despite a relative backlog in understanding the importance of glycans in the immune system, due to its inherent complexity, remarkable findings have been highlighting the essential contributions of glycosylation in the regulatio...


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