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Portuguese recommendations for the use of biological and targeted synthetic dis...

Fernandes, Bruno Miguel; Guimarães, F; Almeida, DE; Neto, A; Tavares-Costa, J; Ribeiro, AR; Quintal, Alberto; Pereira, JP; Silva, L; Nóvoa, TS

Objective: To update the recommendations for the treatment of rheumatoid arthritis (RA) with biological and targeted synthetic disease-modifying antirheumatic drugs (bDMARDs and tsDMARDs), endorsed by the Portuguese Society of Rheumatology (SPR). Methods: These treatment recommendations were formulated by Portuguese rheumatologists taking into account previous recommendations, new literature evidence and consen...


Gender differences in clinical features and outcomes of a Portuguese systemic s...

Freitas, Raquel; Martins, Patrícia; Dourado, Eduardo; Santiago, Tânia; Guimarães, Francisca; Fernandes, Bruno Miguel; Garcia, Salomé; Samões, Beatriz

Evidence for the role of sex in the clinical manifestations of systemic sclerosis (SSc) patients is emerging. Some multicenter cohorts have shown that male SSc patients have more severe disease and worse survival. To assess the differences in clinical manifestations and survival in Portuguese SSc patients according to gender. Data from male and female adult SSc patients included in the Rheumatic Diseases Portug...


Safety and effectiveness of biologic disease-modifying antirheumatic drugs in o...

Freitas, Raquel; Godinho, Fátima; Madeira, Nathalie; Fernandes, Bruno Miguel; Costa, Flávio; Santiago, Mariana; Neto, Agna; Azevedo, Soraia

Background and objective: The number of older patients with rheumatoid arthritis is increasing, but data on drug effectiveness and safety in these patients are scarce. This study assessed the effectiveness and safety of biologic disease-modifying antirheumatic drugs in older patients with rheumatoid arthritis. Methods: This prospective cohort study was based on data recorded in the Rheumatic Diseases Portuguese...


Nature tourism in Peneda-Gerês National Park (Portugal): tourism motivation and...

Fernandes, Bruno Miguel; Liberato, Dália; Teixeira, Ana Sofia; Oliveira, Cláudia Aragão; Silva, Inês; Cerqueira, Isabel Janeiro; Fernandes, Jessica

The increase in demand at the Peneda-Gerês National Park (PNPG), the first protected area created and the only national park in Portugal, demonstrates the growing interest in nature and adventure tourism, both national and international, also confirming current trends in today´s society. However, this research implies the definition of strategies that aim at the protection, conservation and sustainability of th...


Rituximab in connective tissue disease–associated interstitial lung disease

Duarte, Ana Catarina; Cordeiro, Ana; Fernandes, Bruno Miguel; Bernardes, Miguel; Martins, Patrícia; Cordeiro, Inês; Santiago, Tânia; Seixas, Maria Inês

Introduction/objectives: To evaluate rituximab (RTX) effectiveness and safety in patients with interstitial lung disease (ILD) related to connective tissue diseases (CTD). Methods: Retrospective multicenter cohort study, including patients with CTD-ILD, followed in six Portuguese rheumatology departments until November 2018. ILD diagnosis was based on high-resolution CT (HRCT) and/or lung biopsy. Results of HRC...


Sumarização Personalizada e Subjectiva de Texto

Fernandes, Bruno Miguel

Um texto pode ser sumarizado ou resumido, isto é, o seu assunto ou conceito pode ser representado de uma forma mais sucinta. A representação mais comum de um sumário é a escrita, pois é constantemente produzida pelas pessoas, quando estas querem descrever uma determinado assunto. Ao longo dos últimos anos o uso da Internet tem vindo a massificar-se e com isso a quantidade de informação disponível nesta enorme r...

Date: 2014   |   Origin: uBibliorum

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