In recent years, there has been a huge development of innovative engineered nanomaterials with potential use in industrial and biomedical applications. This increased widespread use raised concerns that nanomaterials may elicit human adverse health effects through occupational, environmental or consumer exposure. Many toxicity studies, mainly in vitro, have showed that some nanomaterials, such as carbon nanotub...
As metodologias ativas de ensino-aprendizagem são estratégias para integração de saberes e promoção de atitude crítica e reflexiva no ensino superior, podendo ser utilizadas em atividades de monitoria acadêmica, constituindo-se como um instrumento facilitador da compreensão e produção do conhecimento. O presente trabalho tem como objetivo relatar a experiência de monitores de um programa de monitoria acadêmica ...
Active teaching-learning methodologies are strategies for integrating knowledge and promoting critical and reflective attitude in higher education, and can be used in academic monitoring activities, constituting an instrument that facilitates the understanding and production of knowledge. This paper aims to report the experience of monitors of an academic monitoring program with the use of active methodologies ...
O presente artigo tem como objetivo principal identificar trabalhos, na modalidade de relatos de experiência, que destacam a educação inclusiva na perspectiva da educação especial em contextos de ensino e de aprendizagem matemática, socializados em eventos científicos brasileiros, a partir dos anos 2000. Desse modo, caracteriza-se por um estudo bibliográfico a partir da seleção dos relatos de experiências em an...
Intestinal mucositis (IM) is a common side effect of irinotecan-based chemotherapy. The involvement of inflammatory mediators, such as TNF-α, IL1-β, IL-18 and IL-33, has been demonstrated. However, the role of adaptive immune system cells, whose activation is partially regulated by these cytokines, is yet unknown. Thus, we investigated the role of regulatory T cells (Tregs) in irinotecan-induced IM. C57BL/6 mic...
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Intestinal mucositis (IM) is a common side effect related to anti-cancer chemotherapy based on irinotecan. MI is characterized by severe diarrhea and significantly affects patients' quality of life, increasing morbidity and health costs. Up to 80% of irinotecan-treated patients develop some degree of MI. The pathophysiology of this side effect is not fully understood and, unfortunately, there is no specific and...
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Background: Leprosy is a chronic disease, caused by Mycobacterium leprae, which poses a serious public health problem worldwide. Its high incidence in people under 15 years old in Ceara´ state, Brazil, reflects the difficulty of its control. The spectrum of clinical manifestations is associated with the immune response developed, with the Th1 and Th2 responses being related to the paucibacillary and multibacill...
The aim of the study was to evaluate the resilience level from 19 adolescents between 10 and 15 years old with leprosy, assisted in a reference center in dermatology in the city of Fortaleza. Exploratory and descriptive study with quantitative approach, happened in 2010, in which used one questionnaire and three scales. From total adolescents, 14(73,7%) presented scores between 111 and 154 in the resilience sca...