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The effects of social feedback through the “Like” feature on brain activity: A ...

Dores, Artemisa Rocha; Peixoto, Miguel; Fernandes, Carina; Marques, António; Barbosa, Fernando

Problematic social media (SM) use is a growing concern, particularly among adolescents who are drawn to these platforms for social interactions important to their age group. SM dependence is characterized by excessive, uncontrolled usage that impairs personal, social, and professional aspects. Despite the ongoing debate over recognizing SM addiction as a distinct diagnostic category, the impact of social feedba...


Neurophysiological correlates of near-wins in gambling: A systematic literature...

Dores, Artemisa Rocha; Peixoto, Miguel; Fernandes, Carina; Geraldo, Andreia,; Griffiths, Mark D.; Barbosa, Fernando

Identification of specific patterns of brain activity related to problem gambling may provide a deeper understanding of its underlying mechanisms, highlighting the importance of neurophysiological studies to better understand development and persistence of gambling behavior. The patterns of cognitive functioning have been investigated through electroencephalography (EEG) studies based on the near-win/near-miss ...


Uncertainty deconstructed: conceptual analysis and state-of-the-art review of t...

Botelho, Catarina; Fernandes, Carina; Campos, Carlos; Pasion, Rita; Garcez, Helena; Ferreira-Santos, Fernando; Barbosa, Fernando; Maques-Teixeira, João

Risk and uncertainty are central concepts of decision neuroscience. However, a comprehensive review of the literature shows that most studies define risk and uncertainty in an unclear fashion or use both terms interchangeably, which hinders the integration of the existing findings. We suggest uncertainty as an umbrella term that comprises scenarios characterized by outcome variance where relevant information ab...


Metallopeptidades 2 and 9 genes epigenetically modulate equine endometrial fibr...

Alpoim-Moreira, Joana; Fernandes, Carina; Pimenta, J.; Bliebernicht, Miguel; Rebordão, Maria Rosa; Castelo-Branco, Pedro; Szostek-Mioduchowska, Anna

Endometrium type I (COL1) and III (COL3) collagen accumulation, periglandular fibrosis and mare infertility characterize endometrosis. Metalloproteinase-2 (MMP-2), MMP-9 and tissue inhibitors of metalloproteinases (TIMP-1 and TIMP-2) are involved in collagen turnover. Since epigenetic changes may control fibroproliferative diseases, we hypothesized that epigenetic mechanisms could modulate equine endometrosis. ...


Collagen and microvascularization in placentas from young and older mares

Silva, Ana Catarina Neto; Costa, Ana Luísa; Teixeira, Ana; Alpoim-moreira, Joana; Fernandes, Carina; Fradinho, M.J.; Rebordão, Maria Rosa

In older mares, increasing collagen fibers (fibrosis) in the endometrium and oviduct predisposes to sub-fertility and infertility. In this study, (i) gene transcription of collagen (qPCR: COL1A1, COL1A2, COL3A1, COL5A1); (ii) total collagen protein (hydroxyproline); (iii) collagen distribution (Picrosirius red staining; polarized light microscopy); and (iv) microvascular density (Periodic acid-Schiff staining),...


Collagen Type III as a Possible Blood Biomarker of Fibrosis in Equine Endometrium

Alpoim-Moreira, Joana; Fernandes, Carina; Rebordão, Maria Rosa; Costa, Ana Luísa; BliebernichT, Miguel; Nunes, Telmo; Szóstek-Mioduchowska, Anna

Collagen pathological deposition in equine endometrium (endometrosis) is responsible for infertility. Kenney and Doig’s endometrial biopsy histopathological classification is the gold standard method for endometrosis evaluation, whereby blood biomarkers identification would be less invasive and could provide additional information regarding endometrosis diagnosis and fertility prognosis. This study aimed to ide...


Metallopeptidades 2 and 9 genes epigenetically modulate equine endometrial fibr...

Alpoim-Moreira, Joana; Fernandes, Carina; Pimenta, Jorge; Bliebernicht, Miguel; Rebordão, Maria Rosa; Castelo-Branco, Pedro; Szóstek-Mioduchowska, Anna

Endometrium type I (COL1) and III (COL3) collagen accumulation, periglandular fibrosis and mare infertility characterize endometrosis. Metalloproteinase-2 (MMP-2), MMP-9 and tissue inhibitors of metalloproteinases (TIMP-1 and TIMP-2) are involved in collagen turnover. Since epigenetic changes may control fibroproliferative diseases, we hypothesized that epigenetic mechanisms could modulate equine endometrosis. ...


The Intolerance of Uncertainty Scale (IUS): Translation and adaptation to Europ...

Botelho, Catarina; Barbosa, Fernando; Campos, Carlos; Fernandes, Carina; Ferreira-Santos, Fernando; Marques-Teixeira, João; Pasion, Rita

Intolerance of uncertainty is defined as the individual’s excessive propensity to find unacceptable the probability of a negative event occurring (Dugas et al., 2001b; Buhr & Dugas, 2002). This propensity is brought up bya set of negative beliefs about uncertainty and its consequences (e.g., uncertainty is unacceptable and should be avoided, and/or it leads to the inability to act;Buhr & Dugas, 2002; Freeston e...


A Domain-specific Risk-attitude Scale (DRaS): Translation and adaptation to Eur...

Botelho, Catarina; Barbosa, Fernando; Campos, Carlos; Fernandes, Carina; Ferreira-Santos, Fernando; Marques-Teixeira, João; Pasion, Rita; Seixas, Carlos

Risk attitude, as conceptualized in the classic economic approach, reflects the individual’s sensitivity to disparities in outcomes (i.e., payoffs) variance (Yechiam & Ert, 2011). Brachinger and Weber (1997) further propose that risk attitude depends on the tendency to prefer/avoid risk over certainty. Thus, the degree of risk acceptance underlies risk attitudes. Likewise, Risk-Return models (Weber & Milliman, ...


The impact of different types of shift work on blood pressure and hypertension:...

Madeira, Sara Alexandra Gamboa; Fernandes, Carina; Paiva, Teresa; Santos Moreira, Carlos; Caldeira, Daniel

Shift work (SW) encompasses 20% of the European workforce. Moreover, high blood pressure (BP) remains a leading cause of death globally. This review aimed to synthesize the magnitude of the potential impact of SW on systolic blood pressure (SBP), diastolic blood pressure (DBP) and hypertension (HTN). MEDLINE, EMBASE and CENTRAL databases were searched for epidemiological studies evaluating BP and/or HTN diagnos...


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