Introduction: Pediatric Neurology training is mandatory during Neurology residency in Portugal, yet national data on its quality remain scarce. To address this gap, the Neurology Residents and Early-Career Neurologists Committee (CIREN) of the Portuguese Neurology Society, in collaboration with the Portuguese Society of Pediatric Neurology, developed this study. Methods: An anonymous 33-item online questionnair...
Helicobacter pylori infection has a high prevalence in Portugal and its eradication is a crucial measure in the prevention of gastric cancer. Clarithromycin-based eradication regimens continue to be frequently used in clinical practice.We present a case of a patient who developed severe toxic myopathy associated with the co-administration of simvastatin and clarithromycin, prescribed as part of an Helicobacter ...
ABSTRACT Introduction: Europe is the world's largest producer and exporter of wine, and in recent decades, both have increased in volume and value, driven mainly by the liberalization of international trade. The increasing value of wine exports suggests that higher-quality wines are being produced, which in turn helps attract wine tourists. Wine tourism plays a crucial role in enhancing the visibility and reput...
Migraine is increasingly understood as a disorder of brain network dysfunction, where attack-related cognitive symptoms (attention deficits, slowed processing speed and executive dysfunction) can be as disabling as pain and may persist into the interictal period. Such symptoms are associated with functional and structural changes across the migraine cycle, involving the prefrontal cortex, thalamus, hypothalamus...
The goal of the research is to understand how AI-powered educational platforms can effectively enhance social entrepreneurship skills among higher education students. Specifically, the research aims to: 1. Explore the effectiveness of different AI-driven educational tools in cultivating essential competencies such as innovation, leadership, and ethical decision-making within the context of social entrepreneursh...
Background: Mantle cell lymphoma is usually characterized by an aggressive and recurrent course. Clinical trials and real-world series have demonstrated clinical benefits with the use of ibrutinib as a second-line treatment, compared to later relapses. Objective: To evaluate the Portuguese experience with the use of ibrutinib in patients with relapsed or refractory mantle cell lymphoma since its approval in the...
Certa vez, perguntei a uma criança: "Qual é a forma da Terra?" Ela respondeu: "Na sala de aula, por causa da professora, digo que a Terra é redonda. Mas quando vou de viagem, o carro nunca faz uma curva para cima e para baixo!" Este aparente paradoxo foi o ponto de partida para a elaboração deste livro, intitulado «Aprender com os conhecimentos e as experiências das crianças». A resposta espontânea da criança r...
Lignin, a natural and abundant biopolymer, holds great potential for cosmetic applications. However, its limited solubility and inherently negative charge restrict its use in certain formulations. This is particularly relevant for hair conditioning, where a positively charged polymer is preferred to effectively treat negatively charged damaged hair. To overcome this limitation, lignin extracted from acacia wood...
O Turismo Rural e as Experiências Turísticas são elementos diferenciadores para a competitividade e o desenvolvimento dos territórios rurais, proporcionando aos turistas a oportunidade de interagir com a vida rural e as tradições locais, e permitir que a população residente se envolva na atividade turística. Nesta linha de pensamento, o presente estudo tem como objetivo analisar o desenvolvimento das ilhas de S...
A investigação tem como principal desiderato analisar o potencial da Inteligência Artificial como ferramenta de inovação social no mercado do trabalho, com o propósito de identificar e propor mecanismos para promover a inclusão de diferentes grupos de trabalhadores e aprimorar a qualidade do emprego.