19 documents found, page 1 of 2

Endothelial dysfunction in cardiovascular diseases: mechanisms and in vitro models

Endothelial cells (ECs) are arranged side-by-side to create a semi-permeable monolayer, forming the inner lining of every blood vessel (micro and macrocirculation). Serving as the first barrier for circulating molecules and cells, ECs represent the main regulators of vascular homeostasis being able to respond to environmental changes, either physical or chemical signals, by producing several factors that regula...

Correction to: Endothelial dysfunction in cardiovascular diseases: mechanisms a...

A comprehensive ecotoxicity study of molybdenum disulfide nanosheets versus bul...

The increasing use of molybdenum disulfide (MoS2) nanoparticles (NPs) raises concerns regarding their accumulation in soil ecosystems, with limited studies on their impact on soil organisms. Study aim: To unravel the effects of MoS2 nanosheets (two-dimensional (2D) MoS2 NPs) and bulk MoS2 (156, 313, 625, 1250, 2500 mg/kg) on Enchytraeus crypticus and Folsomia candida. The organisms’ survival and avoidance behav...

Apoio de iniciativas sociais através de financiamento público: uma análise ao s...

O desenvolvimento e sucesso das iniciativas de empreendedorismo social está dependente de um vasto conjunto de instrumentos financeiros que podem ser usados nas fases iniciais e intermédias do lançamento de um projeto, como os subsídios, donativos ou empréstimos, entre outros. No entanto, em Portugal, existem programas de financiamento que potenciam a criação e desenvolvimento de projetos sociais com vista a cr...

Customizing 3D structures of vertically aligned carbon nanotubes to direct neur...

Neural tissue-related illnesses have a high incidence and prevalence in society. Despite intensive research efforts to enhance the regeneration of neural cells into functional tissue, effective treatments are still unavailable. Here, a novel therapeutic approach based on vertically aligned carbon nanotube forests (VA-CNT forests) and periodic VA-CNT micropillars produced by thermal chemical vapor deposition is ...

Telescopic Fingers in Psoriatic Arthritis

A Deep Learning approach to prevent problematic movements of industrial workers...

Nowadays, manufacturing industries still face difficulties applying traditional Work-related MusculoSkeletal Disorders (WMSDs) risk assessment methods due to the high effort required by a continuous data collection when using observational methods. An interesting solution is to adopt Inertial Measurement Units (IMUs) to automate the data collection, thus supporting occupational health professionals. In this pap...

A review of additive manufacturing studies for producing customized ankle-foot ...

Ankle-foot orthoses (AFO) are prescribed to improve the patient’s quality of life. Supporting weak muscles or restraining spastic muscles leads to smoother and more stable locomotion. Commonly, AFO are made using thermoplastic vacuum forming, which requires a long time for production and has limited design options. Additive manufacturing (AM) can solve this problem, leading to a faster and cheaper solution. Thi...

Exposed: The impact of the Covid-19 pandemic on the transgender community in Po...

This study starts with the analysis of international and European directives, as well the as role of international organizations such as the Council of Europe concerning gender identity issues, and the diversity of situations within Europe and the EU itself, by choosing the illustrative example of two countries that obtain the best and the worst results in measuring the rights of transgender people, (Malta and ...

Biomimetic graphene/spongin scaffolds for improved osteoblasts bioactivity via ...

Biomimetics offers excellent prospects for design a novel generation of improved biomaterials. Here the controlled integration of graphene oxide (GO) derivatives with a 3D marine spongin (MS) network is explored to nanoengineer novel smart bio-based constructs for bone tissue engineering. The results point out that 3D MS surfaces can be homogeneously coated by layer-by-layer (LbL) assembly of oppositely charged...