23 documents found, page 1 of 3

Analysis of multiple pesticide and endocrine disruptor residues in drinking wat...

Background: The presence of pesticide residues and endocrine disruptors in sources used for drinking water abstraction has become a significant concern nowadays [1,2]. These substances pose risks to the environment, biodiversity, and public health. Consequently, monitoring these compounds in drinking water is crucial to maintaining their quality and safety. Therefore, there is a need to develop sensitive analyt...

Development of biomimetic human nails using electrospun keratin nanofibers and ...

Introduction: Nail infections, particularly onychomycosis, affect approximately 5.5% of the global population, significantly impacting quality of life. Beyond aesthetic concerns, these conditions cause discomfort, functional impairment, and psychological distress. A major challenge in treatment is the low transungual permeability of the nail plate, restricting drug penetration and reducing therapeutic efficacy....

Optimization of the chromatographic conditions of a multi-residue GC-MS method ...

Background: Nowadays, the presence of pesticide residues and endocrine disruptors in sources for abstraction of drinking water has become a serious concern [1,2]. These classes negatively affect the environment, biodiversity, and public health. In this sense, monitoring these compounds in drinking water is essential to ensure its quality and safety on its use. Therefore, the development of sensitive analytical ...

Epidemiological and clinical aspects of Cutaneous and Mucosal Leishmaniases in ...

Leishmania infantum, a zoonotic vector-born parasite, is endemic in the Mediterranean region, presenting mostly as visceral (VL), but also as cutaneous (CL) and mucosal leishmaniasis (ML). This study aimed to describe the epidemiological and clinical aspects of the CL and ML cases diagnosed in mainland Portugal between 2010 and 2020. Collaboration was requested from every hospital of the Portuguese National Hea...

Biossimilars: Are They So Similar?

Biosimilars are complex proteins of high molecular weight, produced and purified from biologic products, in comparison to generic drugs, biosimilars are biologically similar to the reference drug while a generic is molecularly identical. We focus on the various biosimilar low weight heparins pretending to demonstrate which criteria were chosen to assure the efficacy and safety of these drugs when they were intr...

A ocupação Pré-histórica do Cabeço de Caria Talaia (Sabugal)

Neste artigo realizou-se uma abordagem à ocupação Pré-histórica do Cabeço de Caria Talaia, no concelho do Sabugal (Portugal). A intervenção arqueológica desenvolvida em 2008 e 2009 determinou a natureza e a cronologia dessa ocupação, de uma fase avançada entre o Bronze Médio e os inícios do Bronze Final. Apesar do mau estado de conservação das estruturas, os trabalhos permitiram assinalar um local de habitação ...

Biopharmaceutical formulations for dry powder inhalers

O Lúdico na Aprendizagem do Inglês

O presente relatório teve como propósito compreender como é implementado o ensino precoce do Inglês na Educação Pré-escolar e 1.º Ciclo do Ensino Básico (CEB). Assim, procedeu-se à análise da perceção da professora titular de Inglês sobre o ensino da língua inglesa e da sua prática pedagógica, com o mesmo grupo de crianças; primeiro durante a Educação Pré-escolar quando as crianças tinham 5 anos e subsequenteme...

Improvement of Industrialization Projects Management: An Automotive Industry Ca...

Nowadays, in response to the technological evolution of the markets, organi-zations need to effectively improve their product development process. The product development can be seen as a global project where the industrializa-tion project is a subproject of the product development project. The use of an integrated project management process helps to ensure projects comple-tion according to the schedule plan an...

Que intervenções podem aumentar a adesão parental à vacinação dos filhos?