101 documents found, page 1 of 11
Development of biomimetic human nails using electrospun keratin nanofibers and ...
Fernandes, Diana; Silva, Francisca; Santos, Daniela; Fernandes, Eduarda; Amaral, Maria; Baptista, Rosa; Ribeiro, Artur; Lopes, Carla; Lúcio, MarleneIntroduction: Nail infections, particularly onychomycosis, affect approximately 5.5% of the global population, significantly impacting quality of life. Beyond aesthetic concerns, these conditions cause discomfort, functional impairment, and psychological distress. A major challenge in treatment is the low transungual permeability of the nail plate, restricting drug penetration and reducing therapeutic efficacy....
What are forests for? Social perceptions of the functions of public-managed for...
Figueiredo, Elisabete; Fernandes, Eduarda; Ribeiro, Cristina; Ferreira, CarlaDespite the growing research interest regarding the perceptions of forest-related stakeholders about forest functions and values, the views of social actors not directly involved in forestry have been largely overlooked, particularly in Southern European countries like Portugal. This article addresses this gap by analyzing the social perceptions regarding the functions of the Matas do Litoral, public-managed fo...
2-Styrylchromones as inhibitors of α-amylase and α-glucosidase enzymes for the ...
Santos, Clementina M.M.; Proença, Carina; Freitas, Marisa; Araújo, Alberto N.; Silva, Artur; Fernandes, Eduardaalpha-amylase and alpha-glucosidase are key enzymes implicated in carbohydrate digestion and their inhibition has been suggested as a powerful approach for regulating blood glucose levels. The present work describes for the first time their inhibition by a group of twelve hydroxylated 2-styrylchromones (2-SC). Our findings revealed that 2-SC display strong systematic inhibition of alpha-glucosidase rather than ...
Bioactive compounds and scavenging capacity of Adansonia digitata L. (Baobab fr...
Ferreira da Vinha, Ana; Costa, Anabela S.G.; Pimentel, Filipa B.; Santo, Liliana Espírito; Silva, Carla Sousa e; Freitas, Marisa; Fernandes, EduardaBackground: Baobab fruit is valued for its nutritional and medicinal benefits. Although it is acknowledged that baobab pulp is beneficial for health, studies that link its nutraceutical properties to the ability to eliminate reactive species (ROS and RNS) are scarce. Methods: The nutritional profile and the antioxidant properties of baobab pulp extracts from Angola were evaluated. Thus, for the first time, the ...
Bibliometric Analysis of Sustainable Indicators in Agribusiness
Monteiro, Sónia; Quesado, Patricia; Ribeiro, Verónica; Fernandes, Eduarda; Eugénio, Teresa; Costa, JoãoThe aim of this paper is to analyze the scientific production in the last decade (2011–2022) related to sustainable indicators (environmental, economic, social and ESG—Environmental, Social and Governance) in agribusiness. As methodology, a bibliometric study was carried out on articles from Scopus database. Afterwards, the most cited articles, journals and countries were analyzed, as well as a thematic analysi...
Unveiling the impact of parabens on human neutrophils oxidative burst under hyp...
Ramalho, Ana; Carvalho, Félix; Fernandes, Eduarda; Freitas, MarisaBackground: Parabens, also known as a family of alkyl esters of 4-hydroxybenzoic acid (4-HB), are natural or synthetic compounds that have been used as powerful antimicrobial agents across multiple industries such as cosmetic, pharmaceutical and food industries, since the 1920s [1]. Their widespread use stems from their low cost, broad-spectrum antimicrobial activity, chemical stability, and low risk of trigger...
Exploring quercetin's potential to counteract intestinal pro-inflammatory effec...
Sousa, Adelaide; Azevedo, Rui; Costa, Vera M.; Oliveira, Sara; Viana, Sofia; Reis, Flávio; Almeida, Agostinho; Matafome, Paulo; Dias-Pereira, PatríciaBackground: Silver nanoparticles (AgNP) elicit an intestinal response characterized by vascular and cellular changes, alongside the release of cytokines linked to the activation of the nuclear factor-кB (NF-кB) pathway. Consequently, a search was conducted for a compound capable of counteracting the primary pro-inflammatory effects induced by these nanoparticles [1]. Given the reported anti-inflammatory propert...
A label-free multitechnique approach to characterize the interaction of bioacti...
Fernandes, Eduarda; Costa, Rui Filipe Ramos; Machado, Raúl; Reis, R. L.; Pashkuleva, I.; Lúcio, MarleneExtensive research has been conducted on biomimetic interfaces mimicking the complex and diverse microenvironment of cell membranes to gain insights into bioactive compound interactions and membrane biophysics modulation. The present study proposes an innovative approach that combines five prospective label-free methodologies (derivative spectroscopy, synchrotron small- and wide-angle X-Ray scattering, attenuat...
Manual de Metodologias Participativas – um guia para o envolvimento dos agentes...
Figueiredo, Elisabete; Fernandes, Eduarda; Ferreira, Carla; Gonçalves, Carlos; Ribeiro, CristinaManual de Metodologias Participativas – um guia para o envolvimento dos agentes na gestão da floresta, desenvolvido no âmbito do projeto Share_FOREST, coordenado por Elisabete Figueiredo e Eduarda Fernandes, com coautoria de Carla Ferreira, Carlos Gonçalves e Cristina Ribeiro, e design de Liliana Eusébio.
Nanostructured lipid carriers enriched hydrogels for skin topical administratio...
Lúcio, Marlene; Giannino, Nicole; Barreira, Sérgio; Catita, José; Gonçalves, Hugo; Ribeiro, Artur; Fernandes, Eduarda; Carvalho, Isabel; Pinho, HugoChronic skin exposure to external hostile agents (e.g., UV radiation, microorganisms, and oxidizing chemicals) may increase oxidative stress, causing skin damage and aging. Because of their well-known skincare and protective benefits, quercetin (Q) and omega-3 fatty acids (ω3) have attracted the attention of the dermocosmetic and pharmaceutical sectors. However, both bioactives have inherent properties that lim...