22 documents found, page 1 of 3
Practical Guidance on the Detection of NTRK Fusions in Sarcomas: Current Status...
Fernandes, I; Macedo, D; Gouveia, E; Ferreira, A; Lima, J; Lopez, D; Melo-Alvim, C; Carvalho, A; Tavares, P; Rodrigues-Santos, P; Cardoso, PSarcomas are a rare and heterogeneous group of mesenchymal malignant tumors and account for approximately 1% of all adult cancers and around 20% of all pediatric solid tumors in Europe. Technology advances have enabled a more accurate and efficient characterization of the molecular mechanisms underlying the pathogenesis of sarcoma subtypes and revealed novel and unexpected therapeutic targets with prognostic/pr...
Disclosure of a promising lead to tackle complicated skin and skin structure in...
Gomes, A; Bessa, LJ; Fernandes, I; Ferraz, R; Monteiro, C; Martins, MCL; Mateus, N; Gameiro, P; Teixeira, C; Gomes, PEfficient antibiotics are being exhausted, which compromises the treatment of infections, including complicated skin and skin structure infections (cSSTI) often associated with multidrug resistant (MDR) bacteria, methicillin-resistant S. aureus (MRSA) being the most prevalent. Antimi-crobial peptides (AMP) are being increasingly regarded as the new hope for the post-antibiotic era. Thus, future management of cS...
High-Grade Urothelial Carcinoma in a Kidney Transplant Recipient After JC Virus...
Querido, S; Fernandes, I; Weigert, A; Casimiro, S; Albuquerque, C; Ramos, S; Adragão, T; Luz, I; Paixão, P; Chasqueira, M; Santos, M; Machado, DKidney transplant (KT) recipients have an increased risk for urothelial carcinoma. A role for JC virus (JCV) in human cancers is not yet proved but there is an increasingly reported association between BK virus (BKV) nephropathy and renourinary neoplasms. We report a KT recipient who developed a high-grade urothelial carcinoma 5 years after a diagnosis of JCV nephropathy and 9 years after kidney transplantation...
Erratum to “Gastroenteropancreatic Neuroendocrine Neoplasia Characterization in...
Santos, AP; Vinagre, J; Soares, P; Claro, I; Sanches, AC; Gomes, L; Fernandes, I; Catarino, AL; Preto, J; Pereira, BD; Marques, AP; Rodrigues, FIn the article titled "Gastroenteropancreatic Neuroendocrine Neoplasia Characterization in Portugal: Results from the NETs Study Group of the Portuguese Society of Endocrinology, Diabetes and Metabolism"[1], the affiliation for I. Claro was labeled incorrectly. The correct affiliation of the author I. Claro is Instituto Portugûes de Oncologia de Lisboa, Francisco Gentil (IPOLFG), 1099-023 Lisboa, Portugal.
Inhibitory effect of vinegars on the formation of polycyclic aromatic hydrocarb...
Cordeiro, T; Viegas, Olga; Silva, M; Martins, ZE; Fernandes, I; Ferreira, Isabel; Pinho, Olívia; Nuno Mateus; Conceicao CalhauThe effect of five different vinegars, applied as a seasoning, on the formation of polycyclic aromatic hydrocarbons (PAH) in charcoal-grilled pork loin was investigated. PAH were assayed using acetonitrile based-extraction and high-performance liquid chromatography with fluorescence detection. Unseasoned samples presented a mean value of 31.47 ng g(-1) of PAH4 (sum of benz[a] anthracene, chrysene, benzo[b]fluor...
Gastroenteropancreatic neuroendocrine neoplasia characterization in portugal: R...
Santos, AP; Vinagre, J; Soares, P; Claro, I; Sanches, AC; Gomes, L; Fernandes, I; Catarino, AL; Preto, J; Pereira, BD; Marques, AP; Rodrigues, FBackground. The incidence of gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) has been increasing in the last five decades, but there is no large-scale data regarding these tumours in Portugal. We conducted a cross-sectional, multicentric study in main Portuguese centers to evaluate the clinical, pathological, and therapeutic profile of GEP-NENs. Methods. From November, 2012, to July, 2014, data from ...
Omalizumab for Severe Asthma: Beyond Allergic Asthma.
Loureiro, C; Anmaral, L; Ferreira, A; Lima, R; Pardal, C; Fernandes, I; Semedo, L; Arrobas, ADifferent subsets of asthma patients may be recognized according to the exposure trigger and the frequency and severity of clinical signs and symptoms. Regarding the exposure trigger, generally asthma can be classified as allergic (or atopic) and nonallergic (or nonatopic). Allergic and nonallergic asthma are distinguished by the presence or absence of clinical allergic reaction and in vitro IgE response to spe...
The Portuguese Severe Asthma Registry: Development, Features, and Data Sharing ...
Sá-Sousa, A; Fonseca, JA; Pereira, AM; Ferreira, A; Arrobas, A; Mendes, A; Drummond, M; Videira, W; Costa, T; Farinha, P; Soares, J; Rocha, PThe Portuguese Severe Asthma Registry (Registo de Asma Grave Portugal, RAG) was developed by an open collaborative network of asthma specialists. RAG collects data from adults and pediatric severe asthma patients that despite treatment optimization and adequate management of comorbidities require step 4/5 treatment according to GINA recommendations. In this paper, we describe the development and implementation ...
The Portuguese Severe Asthma Registry: Development, Features, and Data Sharing ...
Sá-Sousa, A; Fonseca, JA; Pereira, AM; Ferreira, A; Arrobas, A; Mendes, A; Drummond, M; Videira, W; Costa, T; Farinha, P; Soares, J; Rocha, PThe Portuguese Severe Asthma Registry (Registo de Asma Grave Portugal, RAG) was developed by an open collaborative network of asthma specialists. RAG collects data from adults and pediatric severe asthma patients that despite treatment optimization and adequate management of comorbidities require step 4/5 treatment according to GINA recommendations. In this paper, we describe the development and implementation ...
Omalizumab for Severe Asthma: Beyond Allergic Asthma
Loureiro, CC; Amaral, L; Ferreira, JA; Lima, R; Pardal, C; Fernandes, I; Semedo, L; Arrobas, ADifferent subsets of asthma patients may be recognized according to the exposure trigger and the frequency and severity of clinical signs and symptoms. Regarding the exposure trigger, generally asthma can be classified as allergic (or atopic) and nonallergic (or nonatopic). Allergic and nonallergic asthma are distinguished by the presence or absence of clinical allergic reaction and in vitro IgE response to spe...